U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Tns4 tensin 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 303517, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tns4provided by RGD
    Official Full Name
    tensin 4provided by RGD
    Primary source
    RGD:1310402
    See related
    EnsemblRapid:ENSRNOG00000027350 AllianceGenome:RGD:1310402
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310402
    Summary
    Predicted to enable actin binding activity. Predicted to be involved in protein localization. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be active in focal adhesion. Orthologous to human TNS4 (tensin 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 12.8), Testes (RPKM 4.6) and 6 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Tns4 in Genome Data Viewer
    Location:
    10q31
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (84518179..84537558, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (84021965..84041346, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (86977504..87001256, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134480868 Neighboring gene uncharacterized LOC134480869 Neighboring gene insulin-like growth factor binding protein 4 Neighboring gene transfer RNA serine (anticodon AGA) 39 Neighboring gene uncharacterized LOC120095183 Neighboring gene C-C motif chemokine receptor 7

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in protein localization ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in focal adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in focal adhesion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    tensin-4
    Names
    C-terminal tensin-like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024881.1NP_001020052.1  tensin-4 precursor

      See identical proteins and their annotated locations for NP_001020052.1

      Status: PROVISIONAL

      Source sequence(s)
      BC097378
      UniProtKB/Swiss-Prot
      G3V8W6, Q4V8I3
      Related
      ENSRNOP00000073971.1, ENSRNOT00000089131.3
      Conserved Domains (2) summary
      cd01213
      Location:583712
      PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
      cl15255
      Location:447560
      SH2; Src homology 2 (SH2) domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      84518179..84537558 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)