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    Igh-6 immunoglobulin heavy chain 6 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 299357, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Igh-6provided by RGD
    Official Full Name
    immunoglobulin heavy chain 6provided by RGD
    Primary source
    RGD:1359202
    See related
    AllianceGenome:RGD:1359202
    Gene type
    protein coding
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    IgM; Igh6; Igh-1a; RGD1359202
    Summary
    Orthologous to several human genes including IGHG1 (immunoglobulin heavy constant gamma 1 (G1m marker)); IGHG2 (immunoglobulin heavy constant gamma 2 (G2m marker)); and IGHG3 (immunoglobulin heavy constant gamma 3 (G3m marker)). [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    not in current annotation release
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    Genomic context

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    Location:
    6q33

    Bibliography

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    Related articles in PubMed

    1. Diversity in the preimmune immunoglobulin repertoire of SHR lines susceptible and resistant to end-organ injury. Gonzalez-Garay ML, et al. Genes Immun, 2014 Dec. PMID 25056448, Free PMC Article
    2. Cloning of cDNA coding for the rat mu heavy chain constant region: differences between rat allotypes. Parker KE, et al. Immunogenetics, 1994. PMID 8276460
    3. Immunoglobulin heavy chain locus of the rat: striking homology to mouse antibody genes. Brüggemann M, et al. Proc Natl Acad Sci U S A, 1986 Aug. PMID 3016742, Free PMC Article
    4. The sclerostin-bone protein interactome. Devarajan-Ketha H, et al. Biochem Biophys Res Commun, 2012 Jan 13. PMID 22206666, Free PMC Article
    5. Identification and characterization of the BRI2 interactome in the brain. Martins F, et al. Sci Rep, 2018 Feb 23. PMID 29476059, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Other Names

    • Ig gamma-2B chain C region
    • Immunoglobulin heavy chain 1a
    • mu heavy chain constant region
    • mu-immunoglobulin

    Clone Names

    • MGC125059

    General protein information

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    Names
    immunoglobulin heavy chain 6
    Ig gamma-2B chain C region
    Immunoglobulin heavy chain 1a
    mu heavy chain constant region
    mu-immunoglobulin

    NCBI Reference Sequences (RefSeq)

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    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001024249.1: Suppressed sequence

      Description
      NM_001024249.1: This RefSeq record was removed by NCBI staff. Contact [email protected] for further information.

    2. NM_001037976.2: Suppressed sequence

      Description
      NM_001037976.2: This RefSeq record was removed by NCBI staff. Contact [email protected] for further information.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P20761.1 GenPept UniProtKB/Swiss-Prot:P20761

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