Ccsap centriole, cilia and spindle-associated protein [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ccsapprovided by RGD
Official Full Name: centriole, cilia and spindle-associated proteinprovided by RGD
Primary source: RGD:1563235
See related: AllianceGenome:RGD:1563235
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1563235
Summary: Predicted to enable microtubule binding activity. Predicted to be involved in mitotic spindle microtubule depolymerization and regulation of mitotic spindle assembly. Predicted to be located in centrosome; cilium; and mitotic spindle astral microtubule. Predicted to be active in axon; ciliary transition zone; and cytoskeleton. Orthologous to human CCSAP (centriole, cilia and spindle associated protein). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Brain (RPKM 88.5), Thymus (RPKM 39.3) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 19q12

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	19	NC_086037.1 (68722417..68740908, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	19	NC_051354.1 (51824954..51843469, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	19	NC_005118.4 (56615326..56634031, complement)

Chromosome 19 - NC_086037.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables microtubule binding	IBA Inferred from Biological aspect of Ancestor more info
enables microtubule binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in mitotic spindle microtubule depolymerization	ISO Inferred from Sequence Orthology more info
involved_in regulation of mitotic spindle assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of mitotic spindle assembly	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in axon	IBA Inferred from Biological aspect of Ancestor more info
located_in axon	ISO Inferred from Sequence Orthology more info
is_active_in axoneme	IBA Inferred from Biological aspect of Ancestor more info
located_in axoneme	ISO Inferred from Sequence Orthology more info
is_active_in centriole	IBA Inferred from Biological aspect of Ancestor more info
located_in centriole	ISO Inferred from Sequence Orthology more info
located_in centrosome	ISO Inferred from Sequence Orthology more info
is_active_in ciliary basal body	IBA Inferred from Biological aspect of Ancestor more info
located_in ciliary basal body	ISO Inferred from Sequence Orthology more info
is_active_in ciliary transition zone	IBA Inferred from Biological aspect of Ancestor more info
located_in ciliary transition zone	ISO Inferred from Sequence Orthology more info
located_in cilium	ISO Inferred from Sequence Orthology more info
located_in mitotic spindle	ISO Inferred from Sequence Orthology more info
located_in mitotic spindle astral microtubule	ISO Inferred from Sequence Orthology more info
is_active_in spindle	IBA Inferred from Biological aspect of Ancestor more info
located_in spindle	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: centriole, cilia and spindle-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001107441.1 → NP_001100911.1 centriole, cilia and spindle-associated protein

See identical proteins and their annotated locations for NP_001100911.1

Status: PROVISIONAL

Source sequence(s)

CH474054

UniProtKB/TrEMBL

A6KIZ1, D3ZZM9

Conserved Domains (1) summary

pfam15748
Location:7 → 251

CCSAP; Centriole, cilia and spindle-associated

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086037.1 Reference GRCr8

Range

68722417..68740908 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006255811.5 → XP_006255873.1 centriole, cilia and spindle-associated protein isoform X1

See identical proteins and their annotated locations for XP_006255873.1

UniProtKB/TrEMBL

A6KIZ1, D3ZZM9

Conserved Domains (1) summary

pfam15748
Location:7 → 251

CCSAP; Centriole, cilia and spindle-associated
XM_063278071.1 → XP_063134141.1 centriole, cilia and spindle-associated protein isoform X1

UniProtKB/TrEMBL

A6KIZ1, D3ZZM9