Prss32 protease, serine, 32 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Prss32provided by RGD
Official Full Name: protease, serine, 32provided by RGD
Primary source: RGD:1311905
See related: EnsemblRapid:ENSRNOG00000029223 AllianceGenome:RGD:1311905
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in plasma membrane. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Liver (RPKM 12.8) and Uterus (RPKM 4.4) See more
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Genomic context

Location:: 10q12

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (13386708..13393195)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (12882504..12888600)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (13196700..13202783)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

D10Got25 (e-PCR)
- UniSTS:114448

RH138419 (e-PCR)
- UniSTS:220506

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables serine-type endopeptidase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in proteolysis	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: protease, serine, 32

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001106983.1 → NP_001100453.1 protease, serine, 32 precursor

See identical proteins and their annotated locations for NP_001100453.1

Status: PROVISIONAL

Source sequence(s)

CH473948

UniProtKB/TrEMBL

A6HCN4, M0RAL3

Related

ENSRNOP00000066564.3, ENSRNOT00000071525.5

Conserved Domains (2) summary

smart00020
Location:53 → 292

Tryp_SPc; Trypsin-like serine protease

cd00190
Location:54 → 295

Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...