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    Pdzd2 PDZ domain containing 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 65034, updated on 9-Dec-2024

    Summary

    Symbol
    Pdzd2provided by RGD
    Full Name
    PDZ domain containing 2provided by RGD
    Primary source
    RGD:619958
    See related
    EnsemblRapid:ENSRNOG00000013140 AllianceGenome:RGD:619958
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Papin; Pdzk3
    Summary
    Predicted to be involved in intracellular signal transduction. Located in several cellular components, including apical part of cell; cell-cell junction; and endoplasmic reticulum. Orthologous to human PDZD2 (PDZ domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 232.3), Heart (RPKM 128.5) and 8 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Pdzd2 in Genome Data Viewer
    Location:
    2q16
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (63111650..63497520, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (61384614..61770516, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (62399748..62520448, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120101086 Neighboring gene golgi phosphoprotein 3 Neighboring gene ferritin light chain 1, pseudogene 14 Neighboring gene uncharacterized LOC100909396 Neighboring gene similar to human chromosome 5 open reading frame 22

    Genomic regions, transcripts, and products

    Bibliography

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in apical part of cell PubMed 
    located_in cell-cell junction PubMed 
    located_in centriolar satellite  
    located_in cytoplasm  
    located_in cytoplasm PubMed 
    located_in cytosol  
    located_in endoplasmic reticulum PubMed 
    located_in extracellular region PubMed 
    located_in intracellular membrane-bounded organelle  
    located_in nucleus PubMed 
    located_in plasma membrane  

    General protein information

    Preferred Names
    PDZ domain-containing protein 2
    Names
    PDZ domain containing 3
    PDZ domain-containing protein 3
    plakophilin-related armadillo repeat protein-interacting PDZ protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_022940.2NP_075229.2  PDZ domain-containing protein 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A0A8I6AIY0, A6KJP6
      Related
      ENSRNOP00000093111.1, ENSRNOT00000108989.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      63111650..63497520 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039103091.2XP_038959019.1  PDZ domain-containing protein 2 isoform X3

      UniProtKB/TrEMBL
      A6KJP6
      Conserved Domains (3) summary
      smart00228
      Location:25872669
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      PHA03247
      Location:8411302
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:446527
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    2. XM_039103090.2XP_038959018.1  PDZ domain-containing protein 2 isoform X2

      UniProtKB/TrEMBL
      A6KJP6
      Conserved Domains (3) summary
      smart00228
      Location:26392721
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      PHA03247
      Location:8931354
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:498579
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    3. XM_039103085.2XP_038959013.1  PDZ domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZMB2, A6KJP6
      Related
      ENSRNOP00000079233.1, ENSRNOT00000105047.2
      Conserved Domains (2) summary
      PHA03247
      Location:9851446
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:590671
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    4. XM_039103086.2XP_038959014.1  PDZ domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZMB2, A6KJP6
      Conserved Domains (2) summary
      PHA03247
      Location:9851446
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:590671
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    5. XM_039103088.2XP_038959016.1  PDZ domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZMB2, A6KJP6
      Conserved Domains (2) summary
      PHA03247
      Location:9851446
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:590671
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    6. XM_039103087.2XP_038959015.1  PDZ domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZMB2, A6KJP6
      Conserved Domains (2) summary
      PHA03247
      Location:9851446
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:590671
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    7. XM_063282504.1XP_063138574.1  PDZ domain-containing protein 2 isoform X4

      UniProtKB/TrEMBL
      A6KJQ0
    8. XM_039103093.2XP_038959021.1  PDZ domain-containing protein 2 isoform X4

      UniProtKB/TrEMBL
      A6KJQ0
      Conserved Domains (2) summary
      PHA03247
      Location:8111272
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:416497
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    9. XM_039103094.2XP_038959022.1  PDZ domain-containing protein 2 isoform X4

      UniProtKB/TrEMBL
      A6KJQ0
      Related
      ENSRNOP00000017937.5, ENSRNOT00000017937.5
      Conserved Domains (2) summary
      PHA03247
      Location:8111272
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:416497
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
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