U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    Rnf187 ring finger protein 187 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 360533, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rnf187provided by RGD
    Official Full Name
    ring finger protein 187provided by RGD
    Primary source
    RGD:1308636
    See related
    AllianceGenome:RGD:1308636
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RACO-1; RGD1308636
    Summary
    Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in several processes, including positive regulation of DNA-templated transcription; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Predicted to be located in cytosol and nucleoplasm. Orthologous to human RNF187 (ring finger protein 187). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 734.5), Testes (RPKM 312.2) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Rnf187 in Genome Data Viewer
    Location:
    10q22
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (44209080..44214979, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (43709493..43715392, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (45273400..45279299, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134480798 Neighboring gene zinc finger protein 39 Neighboring gene butyrophilin like 10 Neighboring gene histone cluster 3, H2ba Neighboring gene H2B.U histone 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding  
    enables ubiquitin-protein transferase activity  
    enables ubiquitin-protein transferase activity  
    Component Evidence Code Pubs
    located_in cytoplasm  
    located_in cytoplasm  
    located_in cytosol  
    located_in nucleoplasm  
    located_in nucleus  
    located_in nucleus  

    General protein information

    Preferred Names
    E3 ubiquitin-protein ligase RNF187
    Names
    RING domain AP1 coactivator 1
    RING-type E3 ubiquitin transferase RNF187
    NP_001157736.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164264.1NP_001157736.1  E3 ubiquitin-protein ligase RNF187

      See identical proteins and their annotated locations for NP_001157736.1

      Status: VALIDATED

      Source sequence(s)
      CK599682, DY320214, DY569693, FM033519
      UniProtKB/Swiss-Prot
      D3Z8N2
      Conserved Domains (1) summary
      pfam00097
      Location:1252
      zf-C3HC4; Zinc finger, C3HC4 type (RING finger)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      44209080..44214979 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    External link. Please review our privacy policy.