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    Pop7 POP7 homolog, ribonuclease P/MRP subunit [ Rattus norvegicus (Norway rat) ]

    Gene ID: 288564, updated on 9-Dec-2024

    Summary

    Official Symbol
    Pop7provided by RGD
    Official Full Name
    POP7 homolog, ribonuclease P/MRP subunitprovided by RGD
    Primary source
    RGD:1306413
    See related
    EnsemblRapid:ENSRNOG00000025310 AllianceGenome:RGD:1306413
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Rpp20
    Summary
    Predicted to enable ribonuclease P RNA binding activity. Predicted to contribute to ribonuclease P activity. Predicted to be involved in tRNA 5'-leader removal. Predicted to be located in nucleolus. Predicted to be part of multimeric ribonuclease P complex and ribonuclease MRP complex. Predicted to be active in nucleus. Orthologous to human POP7 (POP7 homolog, ribonuclease P/MRP subunit). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 139.5), Spleen (RPKM 118.0) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Pop7 in Genome Data Viewer
    Location:
    12q12
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (24826161..24827202)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (19189384..19190425)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (22259713..22260754)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene G protein subunit beta 2 Neighboring gene GRB10 interacting GYF protein 1 Neighboring gene erythropoietin Neighboring gene zonadhesin Neighboring gene uncharacterized LOC134481172

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in biological_process  
    involved_in rRNA processing  
    involved_in tRNA 5'-leader removal  
    involved_in tRNA processing  
    Component Evidence Code Pubs
    located_in cytoplasm  
    located_in intracellular membrane-bounded organelle  
    part_of multimeric ribonuclease P complex  
    part_of nucleolar ribonuclease P complex  
    located_in nucleolus  
    is_active_in nucleus  
    part_of ribonuclease MRP complex  

    General protein information

    Preferred Names
    ribonuclease P protein subunit p20
    Names
    processing of precursor 7, ribonuclease P/MRP subunit
    NP_001099388.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105918.1NP_001099388.1  ribonuclease P protein subunit p20

      See identical proteins and their annotated locations for NP_001099388.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473973
      UniProtKB/TrEMBL
      A6J026, D3ZQJ2
      Related
      ENSRNOP00000111150.1, ENSRNOT00000150874.1
      Conserved Domains (1) summary
      pfam12328
      Location:33133
      Rpp20; Rpp20 subunit of nuclear RNase MRP and P

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      24826161..24827202
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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