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    Trappc4 trafficking protein particle complex subunit 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 367073, updated on 9-Dec-2024

    Summary

    Official Symbol
    Trappc4provided by RGD
    Official Full Name
    trafficking protein particle complex subunit 4provided by RGD
    Primary source
    RGD:1302991
    See related
    EnsemblRapid:ENSRNOG00000011904 AllianceGenome:RGD:1302991
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Sbdn
    Summary
    Predicted to be involved in autophagy; dendrite development; and endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in Golgi stack; dendrite; and synaptic vesicle. Predicted to be part of TRAPP complex. Predicted to be active in postsynaptic density membrane and presynaptic active zone. Orthologous to human TRAPPC4 (trafficking protein particle complex subunit 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 90.9), Brain (RPKM 86.2) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Trappc4 in Genome Data Viewer
    Location:
    8q22
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (53626382..53630042, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (44729458..44733285, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (48723755..48727182, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene hypoxia up-regulated 1 Neighboring gene solute carrier family 37 member 4 Neighboring gene ribosomal protein s25 Neighboring gene centrosomal AT-AC splicing factor Neighboring gene methyltransferase like 9, pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in autophagy  
    involved_in autophagy  
    involved_in autophagy  
    involved_in dendrite development  
    involved_in dendrite development  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport  
    Component Evidence Code Pubs
    located_in Golgi apparatus  
    located_in Golgi membrane  
    located_in Golgi stack  
    located_in Golgi stack  
    part_of TRAPP complex  
    part_of TRAPP complex  
    part_of TRAPP complex  
    part_of TRAPP complex  
    located_in dendrite  
    located_in dendrite  
    located_in endoplasmic reticulum  
    located_in postsynaptic density membrane  
    is_active_in postsynaptic density membrane  
    located_in presynaptic active zone  
    is_active_in presynaptic active zone  
    located_in synapse  
    located_in synaptic vesicle  
    located_in synaptic vesicle  

    General protein information

    Preferred Names
    trafficking protein particle complex subunit 4
    Names
    synbindin
    trafficking protein particle complex 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003708.1NP_001003708.1  trafficking protein particle complex subunit 4

      See identical proteins and their annotated locations for NP_001003708.1

      Status: PROVISIONAL

      Source sequence(s)
      AY373378
      UniProtKB/Swiss-Prot
      Q4G098, Q69BT7
      UniProtKB/TrEMBL
      A0A8I6A204
      Related
      ENSRNOP00000016145.4, ENSRNOT00000016145.8
      Conserved Domains (1) summary
      pfam04099
      Location:3209
      Sybindin; Sybindin-like family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      53626382..53630042 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039081858.2XP_038937786.1  trafficking protein particle complex subunit 4 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A204, A0A8I6GKF4, A6J3Y3
      Related
      ENSRNOP00000093760.1, ENSRNOT00000112974.2
      Conserved Domains (1) summary
      cd14856
      Location:4193
      TRAPPC4_synbindin; Trafficking protein particle complex subunit 4
    2. XM_039081859.2XP_038937787.1  trafficking protein particle complex subunit 4 isoform X2

      Conserved Domains (1) summary
      cl38905
      Location:4599
      longin-like; Longin-like domains
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