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    Sspn sarcospan [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500364, updated on 9-Dec-2024

    Summary

    Symbol
    Sspnprovided by RGD
    Full Name
    sarcospanprovided by RGD
    Primary source
    RGD:1559723
    See related
    EnsemblRapid:ENSRNOG00000001807 AllianceGenome:RGD:1559723
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1559723
    Summary
    Predicted to be located in plasma membrane and transport vesicle. Predicted to be part of dystrophin-associated glycoprotein complex. Predicted to be active in sarcolemma. Orthologous to human SSPN (sarcospan). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 430.8), Muscle (RPKM 241.1) and 4 other tissues See more
    Orthologs
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    Genomic context

    See Sspn in Genome Data Viewer
    Location:
    4q44
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (180620762..180666893)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (178890030..178946267)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (180291389..180325799)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene Ras association domain family member 8 Neighboring gene basic helix-loop-helix family, member e41 Neighboring gene uncharacterized LOC102549898 Neighboring gene uncharacterized LOC134486658 Neighboring gene inositol 1,4,5-trisphosphate receptor, type 2 Neighboring gene uncharacterized LOC134486659

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    part_of dystrophin-associated glycoprotein complex  
    located_in plasma membrane  
    is_active_in sarcolemma  
    located_in sarcolemma  
    located_in transport vesicle  
    located_in transport vesicle  

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109255.2 → NP_001102725.1  sarcospan

      See identical proteins and their annotated locations for NP_001102725.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      A6IN14, D4ABT9
      Related
      ENSRNOP00000002465.3, ENSRNOT00000002465.6
      Conserved Domains (1) summary
      pfam04103
      Location:37 → 183
      CD20; CD20-like family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      180620762..180666893
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039108232.2 → XP_038964160.1  sarcospan isoform X2

      Conserved Domains (1) summary
      pfam04103
      Location:9 → 107
      CD20; CD20-like family
    2. XM_039108233.2 → XP_038964161.1  sarcospan isoform X3

      Conserved Domains (1) summary
      pfam04103
      Location:37 → 96
      CD20; CD20-like family
    3. XM_017592843.3 → XP_017448332.1  sarcospan isoform X1

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