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    Ahnak2 AHNAK nucleoprotein 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 314478, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ahnak2provided by RGD
    Official Full Name
    AHNAK nucleoprotein 2provided by RGD
    Primary source
    RGD:1309696
    See related
    AllianceGenome:RGD:1309696
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309696
    Summary
    Predicted to be located in several cellular components, including cytoplasmic vesicle membrane; cytosol; and myofibril. Orthologous to human AHNAK2 (AHNAK nucleoprotein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Uterus (RPKM 113.4), Lung (RPKM 89.0) and 8 other tissues See more
    Orthologs
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    Genomic context

    See Ahnak2 in Genome Data Viewer
    Location:
    6q32
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (137648867..137697580, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (131830668..131876311, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (137335273..137380219, complement)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene centrosomal protein 170B Neighboring gene uncharacterized LOC134479263 Neighboring gene phospholipase D family, member 4 Neighboring gene clathrin binding box of aftiphilin containing 1 Neighboring gene cell division cycle associated 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      137648867..137697580 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039113411.2XP_038969339.1  protein AHNAK2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AAE1
      Conserved Domains (2) summary
      COG2911
      Location:49705863
      TamB; Autotransporter translocation and assembly factor TamB [Intracellular trafficking, secretion, and vesicular transport]
      cd00992
      Location:112191
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    2. XM_063262711.1XP_063118781.1  protein AHNAK2 isoform X4

    3. XM_063262710.1XP_063118780.1  protein AHNAK2 isoform X3

      UniProtKB/TrEMBL
      A0A8I6AAE1
    4. XM_039113413.2XP_038969341.1  protein AHNAK2 isoform X2

      UniProtKB/TrEMBL
      A0A8I6AAE1
      Conserved Domains (2) summary
      COG2911
      Location:48705763
      TamB; Autotransporter translocation and assembly factor TamB [Intracellular trafficking, secretion, and vesicular transport]
      cd00992
      Location:1291
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    5. XM_039113412.2XP_038969340.1  protein AHNAK2 isoform X2

      UniProtKB/TrEMBL
      A0A8I6AAE1
      Conserved Domains (2) summary
      COG2911
      Location:48705763
      TamB; Autotransporter translocation and assembly factor TamB [Intracellular trafficking, secretion, and vesicular transport]
      cd00992
      Location:1291
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...