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    Zbtb38 zinc finger and BTB domain containing 38 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 315936, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zbtb38provided by RGD
    Official Full Name
    zinc finger and BTB domain containing 38provided by RGD
    Primary source
    RGD:1310136
    See related
    EnsemblRapid:ENSRNOG00000012386 AllianceGenome:RGD:1310136
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310136
    Summary
    Enables DNA-binding transcription factor activity. Involved in positive regulation of transcription by RNA polymerase II. Located in nucleus. Orthologous to human ZBTB38 (zinc finger and BTB domain containing 38). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 63.6), Heart (RPKM 62.1) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Zbtb38 in Genome Data Viewer
    Location:
    8q31
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (106124181..106231215, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (97284617..97288518, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (104566999..104694890, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 78 Neighboring gene uncharacterized LOC120094237 Neighboring gene RAS p21 protein activator 2 Neighboring gene peptidyl-prolyl cis-trans isomerase D pseudogene Neighboring gene uncharacterized LOC100909637 Neighboring gene uncharacterized LOC134480088 Neighboring gene 2-phosphoxylose phosphatase 1 Neighboring gene uncharacterized LOC120094379

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in DNA damage response  
    involved_in DNA damage response  
    involved_in DNA damage response  
    involved_in biological_process  
    involved_in negative regulation of DNA-templated transcription  
    involved_in negative regulation of DNA-templated transcription  
    involved_in negative regulation of DNA-templated transcription  
    involved_in positive regulation of transcription by RNA polymerase II PubMed 
    involved_in regulation of DNA replication  
    involved_in regulation of DNA replication  
    involved_in regulation of DNA replication  
    involved_in regulation of DNA-templated transcription  
    Component Evidence Code Pubs
    located_in chromosome  
    located_in nucleoplasm  
    located_in nucleoplasm  
    located_in nucleus PubMed 
    located_in nucleus  

    General protein information

    Preferred Names
    zinc finger and BTB domain-containing protein 38
    Names
    zenon
    zinc finger protein expressed in neurons
    zinc finger transcription factor Kaiso

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012471.2NP_001012489.2  zinc finger and BTB domain-containing protein 38

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A6I286, M0RCM7
      Conserved Domains (5) summary
      sd00017
      Location:10191039
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18223
      Location:15128
      BTB_POZ_ZBTB38_CIBZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 38 (ZBTB38)
      pfam00096
      Location:10451067
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:10321055
      zf-H2C2_2; Zinc-finger double domain
      pfam15909
      Location:308401
      zf-C2H2_8; C2H2-type zinc ribbon

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      106124181..106231215 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063265581.1XP_063121651.1  zinc finger and BTB domain-containing protein 38 isoform X2

      UniProtKB/TrEMBL
      A6I286, M0RCM7
      Related
      ENSRNOP00000103824.1, ENSRNOT00000121360.1
    2. XM_063265579.1XP_063121649.1  zinc finger and BTB domain-containing protein 38 isoform X2

      UniProtKB/TrEMBL
      A6I286, M0RCM7
      Related
      ENSRNOP00000095257.1, ENSRNOT00000102946.3
    3. XM_063265578.1XP_063121648.1  zinc finger and BTB domain-containing protein 38 isoform X2

      UniProtKB/TrEMBL
      A6I286, M0RCM7
      Related
      ENSRNOP00000081285.1, ENSRNOT00000111528.2
    4. XM_063265582.1XP_063121652.1  zinc finger and BTB domain-containing protein 38 isoform X2

      UniProtKB/TrEMBL
      A6I286, M0RCM7
      Related
      ENSRNOP00000067350.1, ENSRNOT00000016625.8
    5. XM_063265575.1XP_063121645.1  zinc finger and BTB domain-containing protein 38 isoform X1

      UniProtKB/TrEMBL
      A6I286
    6. XM_063265584.1XP_063121654.1  zinc finger and BTB domain-containing protein 38 isoform X2

      UniProtKB/TrEMBL
      A6I286, M0RCM7
      Related
      ENSRNOP00000108939.1, ENSRNOT00000154527.1
    7. XM_063265583.1XP_063121653.1  zinc finger and BTB domain-containing protein 38 isoform X2

      UniProtKB/TrEMBL
      A6I286, M0RCM7
    8. XM_063265576.1XP_063121646.1  zinc finger and BTB domain-containing protein 38 isoform X2

      UniProtKB/TrEMBL
      A6I286, M0RCM7
      Related
      ENSRNOP00000098232.1, ENSRNOT00000120592.2
    9. XM_063265577.1XP_063121647.1  zinc finger and BTB domain-containing protein 38 isoform X2

      UniProtKB/TrEMBL
      A6I286, M0RCM7
    10. XM_063265580.1XP_063121650.1  zinc finger and BTB domain-containing protein 38 isoform X2

      UniProtKB/TrEMBL
      A6I286, M0RCM7

    RNA

    1. XR_010053975.1 RNA Sequence

    2. XR_010053976.1 RNA Sequence

    3. XR_010053974.1 RNA Sequence

    4. XR_010053973.1 RNA Sequence

    5. XR_010053978.1 RNA Sequence

    6. XR_010053977.1 RNA Sequence

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