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    Zscan20 zinc finger and SCAN domain containing 20 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500549, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zscan20provided by RGD
    Official Full Name
    zinc finger and SCAN domain containing 20provided by RGD
    Primary source
    RGD:1562996
    See related
    EnsemblRapid:ENSRNOG00000005886 AllianceGenome:RGD:1562996
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1562996
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZSCAN20 (zinc finger and SCAN domain containing 20). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 31.6), Heart (RPKM 28.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zscan20 in Genome Data Viewer
    Location:
    5q36
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (146214023..146240678, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (140926596..140956285, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (146760822..146788945, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene CUB and Sushi multiple domains 2 Neighboring gene high-mobility group box 4 Neighboring gene uncharacterized LOC134486995 Neighboring gene toll-like receptor 12 Neighboring gene polyhomeotic homolog 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger and SCAN domain containing 20; zinc finger and SCAN domain-containing protein 20
    Names
    zinc finger and SCAN domains 20

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001431230.1 → NP_001418159.1  zinc finger and SCAN domain containing 20 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      D3ZCC2

    2. NM_001431231.1 → NP_001418160.1  zinc finger and SCAN domain containing 20 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005

    3. NM_001431232.1 → NP_001418161.1  zinc finger and SCAN domain containing 20 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      146214023..146240678 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063288626.1 → XP_063144696.1  zinc finger and SCAN domain-containing protein 20 isoform X3

    2. XM_063288625.1 → XP_063144695.1  zinc finger and SCAN domain-containing protein 20 isoform X2

    3. XM_008764178.4 → XP_008762400.2  zinc finger and SCAN domain-containing protein 20 isoform X1

      Related
      ENSRNOP00000008887.7, ENSRNOT00000008887.8
      Conserved Domains (4) summary
      COG5048
      Location:818 → 1120
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:1042 → 1062
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02023
      Location:136 → 221
      SCAN; SCAN domain
      pfam13837
      Location:410 → 491
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

    4. XM_063288627.1 → XP_063144697.1  zinc finger and SCAN domain-containing protein 20 isoform X4

      Related
      ENSRNOP00000099859.1, ENSRNOT00000157762.1

    5. XM_063288628.1 → XP_063144698.1  zinc finger and SCAN domain-containing protein 20 isoform X4

      UniProtKB/TrEMBL
      D3ZCC2
    Nucleotide Protein Strain
    Heading Accession and Version

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