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    Eif3m eukaryotic translation initiation factor 3, subunit M [ Rattus norvegicus (Norway rat) ]

    Gene ID: 295975, updated on 4-Jan-2025

    Summary

    Official Symbol
    Eif3mprovided by RGD
    Official Full Name
    eukaryotic translation initiation factor 3, subunit Mprovided by RGD
    Primary source
    RGD:1565840
    See related
    EnsemblRapid:ENSRNOG00000012738 AllianceGenome:RGD:1565840
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1565840
    Summary
    Predicted to enable translation initiation factor binding activity. Predicted to contribute to translation initiation factor activity. Predicted to be involved in cytoplasmic translational initiation. Predicted to act upstream of or within translation. Predicted to be part of eukaryotic translation initiation factor 3 complex, eIF3m. Orthologous to human EIF3M (eukaryotic translation initiation factor 3 subunit M). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Biased expression in Spleen (RPKM 851.0), Thymus (RPKM 842.7) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Eif3m in Genome Data Viewer
    Location:
    3q33
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (111879589..111897193, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (91424754..91442358, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (94990086..95007690, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L17, pseudogene 17 Neighboring gene coiled-coil domain containing 73 Neighboring gene uncharacterized LOC134486134 Neighboring gene gamma-aminobutyric acid receptor-associated protein-like 2 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    part_of eukaryotic 43S preinitiation complex  
    part_of eukaryotic 48S preinitiation complex  
    part_of eukaryotic translation initiation factor 3 complex  
    part_of eukaryotic translation initiation factor 3 complex  
    part_of eukaryotic translation initiation factor 3 complex, eIF3m  

    General protein information

    Preferred Names
    eukaryotic translation initiation factor 3 subunit M
    NP_001161995.1
    XP_038960460.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001168523.1NP_001161995.1  eukaryotic translation initiation factor 3 subunit M isoform 1

      See identical proteins and their annotated locations for NP_001161995.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A6HNV6, D3ZAZ0
      Related
      ENSRNOP00000017409.7, ENSRNOT00000017409.9
      Conserved Domains (1) summary
      smart00088
      Location:269357
      PINT; motif in proteasome subunits, Int-6, Nip-1 and TRIP-15
    2. NM_001429982.1NP_001416911.1  eukaryotic translation initiation factor 3 subunit M isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A0A8I5ZR56

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      111879589..111897193 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039104532.2XP_038960460.1  eukaryotic translation initiation factor 3 subunit M isoform X1

      Conserved Domains (1) summary
      smart00088
      Location:206294
      PINT; motif in proteasome subunits, Int-6, Nip-1 and TRIP-15
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