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    Atrnl1 attractin like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 307992, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Atrnl1provided by RGD
    Official Full Name
    attractin like 1provided by RGD
    Primary source
    RGD:1563485
    See related
    EnsemblRapid:ENSRNOG00000017406 AllianceGenome:RGD:1563485
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1563485
    Summary
    Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Orthologous to human ATRNL1 (attractin like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 427.0), Brain (RPKM 323.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Atrnl1 in Genome Data Viewer
    Location:
    1q55
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (266676051..267216847)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (256670976..257219291)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (278546113..279098977)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102551125 Neighboring gene uncharacterized LOC134485260 Neighboring gene ribosomal protein S19, pseudogene 14 Neighboring gene uncharacterized LOC134485261 Neighboring gene uncharacterized LOC120097692 Neighboring gene uncharacterized LOC108349828 Neighboring gene uncharacterized LOC102556644 Neighboring gene GDNF family receptor alpha 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Melanocortin receptors and their accessory proteins. Cooray SN, et al. Mol Cell Endocrinol, 2011 Jan 15. PMID 20654690
    2. Characterization of a novel binding partner of the melanocortin-4 receptor: attractin-like protein. Haqq AM, et al. Biochem J, 2003 Dec 15. PMID 14531729, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    attractin like 1; attractin-like protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001431114.1 → NP_001418043.1  attractin like 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I5Y1Z3, F1M3T8

    2. NM_001431115.1 → NP_001418044.1  attractin like 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      F1M3T8

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      266676051..267216847
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008760587.4 → XP_008758809.2  attractin-like protein 1 isoform X1

      Related
      ENSRNOP00000078125.1, ENSRNOT00000118477.2
      Conserved Domains (8) summary
      PLN02153
      Location:349 → 615
      PLN02153; epithiospecifier protein
      cd00041
      Location:92 → 207
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00055
      Location:1011 → 1056
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      sd00038
      Location:520 → 573
      Kelch; KELCH repeat [structural motif]
      pfam01437
      Location:887 → 936
      PSI; Plexin repeat
      pfam13854
      Location:351 → 391
      Kelch_5; Kelch motif
      cl02432
      Location:746 → 872
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
      cl19567
      Location:234 → 279
      DSL; Delta serrate ligand

    2. XM_039095274.2 → XP_038951202.1  attractin-like protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8I6AGE2, F1M3T8
      Related
      ENSRNOP00000087353.1, ENSRNOT00000111371.2
      Conserved Domains (8) summary
      PLN02153
      Location:349 → 615
      PLN02153; epithiospecifier protein
      cd00041
      Location:92 → 207
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00055
      Location:1011 → 1056
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      sd00038
      Location:520 → 573
      Kelch; KELCH repeat [structural motif]
      pfam01437
      Location:887 → 936
      PSI; Plexin repeat
      pfam13854
      Location:351 → 391
      Kelch_5; Kelch motif
      cl02432
      Location:746 → 872
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
      cl19567
      Location:234 → 279
      DSL; Delta serrate ligand

    3. XM_063281046.1 → XP_063137116.1  attractin-like protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZVB8, F1M3T8

    4. XM_039095277.2 → XP_038951205.1  attractin-like protein 1 isoform X4

      UniProtKB/TrEMBL
      F1M3T8
      Related
      ENSRNOP00000023414.8, ENSRNOT00000023414.9
      Conserved Domains (8) summary
      PLN02153
      Location:349 → 615
      PLN02153; epithiospecifier protein
      cd00041
      Location:92 → 207
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00055
      Location:1011 → 1056
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      sd00038
      Location:520 → 573
      Kelch; KELCH repeat [structural motif]
      pfam01437
      Location:887 → 936
      PSI; Plexin repeat
      pfam13854
      Location:351 → 391
      Kelch_5; Kelch motif
      cl02432
      Location:746 → 872
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
      cl19567
      Location:234 → 279
      DSL; Delta serrate ligand

    5. XM_039095283.2 → XP_038951211.1  attractin-like protein 1 isoform X5

      Conserved Domains (8) summary
      cd03597
      Location:601 → 727
      CLECT_attractin_like; C-type lectin-like domain (CTLD) of the type found in human and mouse attractin (AtrN) and attractin-like protein (ALP)
      PLN02153
      Location:204 → 470
      PLN02153; epithiospecifier protein
      cd00055
      Location:866 → 911
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      sd00038
      Location:375 → 428
      Kelch; KELCH repeat [structural motif]
      pfam01437
      Location:742 → 791
      PSI; Plexin repeat
      pfam13854
      Location:206 → 246
      Kelch_5; Kelch motif
      cl00049
      Location:3 → 62
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cl19567
      Location:89 → 134
      DSL; Delta serrate ligand
    Nucleotide Protein Strain
    Heading Accession and Version

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