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    Ube2d2b ubiquitin-conjugating enzyme E2D 2B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 79435, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ube2d2bprovided by RGD
    Official Full Name
    ubiquitin-conjugating enzyme E2D 2Bprovided by RGD
    Primary source
    RGD:69425
    See related
    EnsemblRapid:ENSRNOG00000082439 AllianceGenome:RGD:69425
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ube2d2; Ube2d4; RGD69425
    Summary
    Predicted to enable ubiquitin conjugating enzyme activity. Involved in cellular response to arsenite(3-) and cellular response to cadmium ion. Predicted to be active in nucleus. Orthologous to human UBE2D4 (ubiquitin conjugating enzyme E2 D4). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See Ube2d2b in Genome Data Viewer
    Location:
    14p22
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (2060926..2062400, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (1915999..1917473, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (2933097..2934571, complement)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene RuvB-like AAA ATPase 2, pseudogene 1 Neighboring gene 40S ribosomal protein S26-like Neighboring gene small ribosomal subunit protein eS26-like Neighboring gene ecotropic viral integration site 5 Neighboring gene growth factor independent 1 transcriptional repressor Neighboring gene RNA polymerase II associated protein 2 Neighboring gene glomulin, FKBP associated protein

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding  
    enables transferase activity  
    enables ubiquitin conjugating enzyme activity  
    enables ubiquitin conjugating enzyme activity  
    enables ubiquitin-protein transferase activity  
    Component Evidence Code Pubs
    is_active_in nucleus  

    General protein information

    Preferred Names
    ubiquitin-conjugating enzyme E2 D2B
    Names
    E2 ubiquitin-conjugating enzyme D2B
    E2(17)KB 2B
    ubiquitin carrier protein D2B
    ubiquitin-conjugating enzyme E2(17)KB 2B
    ubiquitin-conjugating enzyme E2-17 kDa 2B
    ubiquitin-conjugating enzyme E2D 2
    ubiquitin-conjugating enzyme E2D 4 (putative)
    ubiquitin-protein ligase D2B
    NP_112263.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031001.2NP_112263.1  ubiquitin-conjugating enzyme E2 D2B

      See identical proteins and their annotated locations for NP_112263.1

      Status: PROVISIONAL

      Source sequence(s)
      BC078808
      UniProtKB/Swiss-Prot
      P70711
      UniProtKB/TrEMBL
      A0A8I5ZTI3, A6KPH8
      Related
      ENSRNOP00000101492.1, ENSRNOT00000162982.1
      Conserved Domains (1) summary
      cl00154
      Location:1146
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      2060926..2062400 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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