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    Rtn4ip1 reticulon 4 interacting protein 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 309912, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rtn4ip1provided by RGD
    Official Full Name
    reticulon 4 interacting protein 1provided by RGD
    Primary source
    RGD:1563384
    See related
    EnsemblRapid:ENSRNOG00000000279 AllianceGenome:RGD:1563384
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1563384
    Summary
    Predicted to enable NADPH dehydrogenase (quinone) activity. Predicted to be involved in regulation of dendrite development and ubiquinone biosynthetic process. Predicted to be located in mitochondrial outer membrane. Predicted to be active in mitochondrial matrix. Human ortholog(s) of this gene implicated in optic atrophy 10. Orthologous to human RTN4IP1 (reticulon 4 interacting protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 97.6), Muscle (RPKM 60.5) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Rtn4ip1 in Genome Data Viewer
    Location:
    20q13
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (48964903..49004235)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (47382251..47422747)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (48881124..48924921)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134483830 Neighboring gene nuclear speckle splicing regulatory protein 1, pseudogene 1 Neighboring gene glutaminyl-tRNA amidotransferase subunit QRSL1 Neighboring gene crystallin beta-gamma domain containing 1 Neighboring gene heat shock cognate 71 kDa protein-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables NADPH dehydrogenase (quinone) activity  
    enables zinc ion binding  
    Component Evidence Code Pubs
    is_active_in mitochondrial matrix  
    located_in mitochondrial outer membrane  
    located_in mitochondrion PubMed 

    General protein information

    Preferred Names
    reticulon-4-interacting protein 1, mitochondrial

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107644.3NP_001101114.1  reticulon-4-interacting protein 1, mitochondrial

      See identical proteins and their annotated locations for NP_001101114.1

      Status: PROVISIONAL

      Source sequence(s)
      BC166465
      UniProtKB/TrEMBL
      A6K6W3, B2GUZ6, F7ESF4
      Related
      ENSRNOP00000109113.1, ENSRNOT00000132854.1
      Conserved Domains (2) summary
      cd08248
      Location:43394
      RTN4I1; Human Reticulon 4 Interacting Protein 1
      COG0604
      Location:43395
      Qor; NADPH:quinone reductase or related Zn-dependent oxidoreductase [Energy production and conversion, General function prediction only]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      48964903..49004235
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063279188.1XP_063135258.1  reticulon-4-interacting protein 1, mitochondrial isoform X1

    2. XM_063279190.1XP_063135260.1  reticulon-4-interacting protein 1, mitochondrial isoform X3

    3. XM_063279189.1XP_063135259.1  reticulon-4-interacting protein 1, mitochondrial isoform X2

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