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    Cacng1 calcium voltage-gated channel auxiliary subunit gamma 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 29658, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cacng1provided by RGD
    Official Full Name
    calcium voltage-gated channel auxiliary subunit gamma 1provided by RGD
    Primary source
    RGD:2249
    See related
    EnsemblRapid:ENSRNOG00000003245 AllianceGenome:RGD:2249
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Cacng
    Summary
    Enables calcium channel regulator activity. Involved in regulation of calcium ion transmembrane transport via high voltage-gated calcium channel. Part of L-type voltage-gated calcium channel complex. Human ortholog(s) of this gene implicated in malignant hyperthermia. Orthologous to human CACNG1 (calcium voltage-gated channel auxiliary subunit gamma 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 1296.3) See more
    Orthologs
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    Genomic context

    See Cacng1 in Genome Data Viewer
    Location:
    10q32.1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (93152558..93165246, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (92652924..92665612, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (95921479..95934170, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene proteasome 26S subunit, non-ATPase 12 Neighboring gene helicase with zinc finger Neighboring gene uncharacterized LOC120095197 Neighboring gene uncharacterized LOC134480890 Neighboring gene calcium voltage-gated channel auxiliary subunit gamma 4 Neighboring gene uncharacterized LOC108352150

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    part_of L-type voltage-gated calcium channel complex  
    part_of L-type voltage-gated calcium channel complex PubMed 
    part_of L-type voltage-gated calcium channel complex  
    located_in T-tubule  
    located_in plasma membrane  
    located_in sarcolemma  
    located_in sarcolemma  
    part_of voltage-gated calcium channel complex  

    General protein information

    Preferred Names
    voltage-dependent calcium channel gamma-1 subunit
    Names
    calcium channel, voltage-dependent, gamma subunit 1
    dihydropyridine-sensitive L-type, skeletal muscle calcium channel subunit gamma

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019255.1NP_062128.1  voltage-dependent calcium channel gamma-1 subunit

      See identical proteins and their annotated locations for NP_062128.1

      Status: PROVISIONAL

      Source sequence(s)
      Y09453
      UniProtKB/Swiss-Prot
      P97707
      UniProtKB/TrEMBL
      A6HK85, G3V6E5
      Related
      ENSRNOP00000004349.1, ENSRNOT00000004349.6
      Conserved Domains (1) summary
      cl21598
      Location:21188
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      93152558..93165246 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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