Zfp64 zinc finger protein 64 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Zfp64provided by RGD
Official Full Name: zinc finger protein 64provided by RGD
Primary source: RGD:1307948
See related: EnsemblRapid:ENSRNOG00000012762 AllianceGenome:RGD:1307948
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable metal ion binding activity. Predicted to be involved in mesenchymal cell differentiation and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within positive regulation of mRNA splicing, via spliceosome. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Orthologous to human ZFP64 (ZFP64 zinc finger protein). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 28.1), Heart (RPKM 24.9) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 3q42

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (178085604..178114557, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (157666819..157695774, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (165713070..165741932, complement)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

D3Got158 (e-PCR)
- UniSTS:112286

AA799851 (e-PCR)
- UniSTS:250319

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in mesenchymal cell differentiation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of mRNA splicing, via spliceosome	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: zinc finger protein 64

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001012093.1 → NP_001012093.1 zinc finger protein 64

See identical proteins and their annotated locations for NP_001012093.1

Status: PROVISIONAL

Source sequence(s)

BC085820

UniProtKB/TrEMBL

A0A8I6A5Z8, A6JXQ7, F7ETK0, Q5U2X9

Related

ENSRNOP00000017063.5, ENSRNOT00000017063.8

Conserved Domains (4) summary

COG5048
Location:151 → 450

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:177 → 197

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam13465
Location:161 → 186

zf-H2C2_2; Zinc-finger double domain

pfam13912
Location:424 → 450

zf-C2H2_6; C2H2-type zinc finger