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    Rbbp9 RB binding protein 9, serine hydrolase [ Rattus norvegicus (Norway rat) ]

    Gene ID: 29459, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Rbbp9provided by RGD
    Official Full Name
    RB binding protein 9, serine hydrolaseprovided by RGD
    Primary source
    RGD:3542
    See related
    EnsemblRapid:ENSRNOG00000007972 AllianceGenome:RGD:3542
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable hydrolase activity. Involved in regulation of cell population proliferation. Predicted to be located in nucleoplasm. Orthologous to human RBBP9 (RB binding protein 9, serine hydrolase). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 126.8), Adrenal (RPKM 104.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Rbbp9 in Genome Data Viewer
    Location:
    3q41
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (152378426..152392370, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (131925095..131939042, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (138701579..138708332, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene double zinc ribbon and ankyrin repeat domains 1 Neighboring gene RNA polymerase III subunit F Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene Sec23 homolog B, COPII coat complex component Neighboring gene small integral membrane protein 26 Neighboring gene D-aminoacyl-tRNA deacylase 1 Neighboring gene uncharacterized LOC134486168 Neighboring gene receptor for activated C kinase 1, pseudogene 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A retinoblastoma-binding protein that affects cell-cycle control and confers transforming ability. Woitach JT, et al. Nat Genet, 1998 Aug. PMID 9697699
    2. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC124617

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of gene expression IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within positive regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of cell population proliferation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to nematode IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to nematode ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in type II pneumocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within type II pneumocyte differentiation ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    serine hydrolase RBBP9
    Names
    B5T-overexpressed gene protein
    RBBP-9
    putative hydrolase RBBP9
    retinoblastoma-binding protein 9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019219.3 → NP_062092.2  serine hydrolase RBBP9

      See identical proteins and their annotated locations for NP_062092.2

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/Swiss-Prot
      O88350, Q3T1H7
      UniProtKB/TrEMBL
      A0A8L2Q4I8, A6K763
      Related
      ENSRNOP00000010678.5, ENSRNOT00000010678.6
      Conserved Domains (1) summary
      cl21494
      Location:8 → 173
      Abhydrolase; alpha/beta hydrolases

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      152378426..152392370 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039104444.1 → XP_038960372.1  serine hydrolase RBBP9 isoform X1

      Conserved Domains (1) summary
      cl21494
      Location:1 → 130
      Abhydrolase; alpha/beta hydrolases

    2. XM_063283215.1 → XP_063139285.1  serine hydrolase RBBP9 isoform X1

    3. XM_039104445.2 → XP_038960373.1  serine hydrolase RBBP9 isoform X2

      Conserved Domains (1) summary
      cl21494
      Location:1 → 115
      Abhydrolase; alpha/beta hydrolases
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O88350.2 GenPept UniProtKB/Swiss-Prot:O88350

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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