U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Stt3b STT3 oligosaccharyltransferase complex catalytic subunit B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363160, updated on 27-Dec-2024

    Summary

    Official Symbol
    Stt3bprovided by RGD
    Official Full Name
    STT3 oligosaccharyltransferase complex catalytic subunit Bprovided by RGD
    Primary source
    RGD:1311563
    See related
    EnsemblRapid:ENSRNOG00000011922 AllianceGenome:RGD:1311563
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1311563
    Summary
    Predicted to enable dolichyl-diphosphooligosaccharide-protein glycotransferase activity. Predicted to be involved in protein catabolic process; protein modification process; and response to unfolded protein. Predicted to be located in endoplasmic reticulum. Predicted to be part of oligosaccharyltransferase complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ix. Orthologous to human STT3B (STT3 oligosaccharyltransferase complex catalytic subunit B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 551.6), Kidney (RPKM 401.0) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Stt3b in Genome Data Viewer
    Location:
    8q32
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (123806836..123872179, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (114928678..114994027, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (123303910..123370729, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene oxysterol binding protein-like 10 Neighboring gene uncharacterized LOC108351789 Neighboring gene uncharacterized LOC120094279 Neighboring gene uncharacterized LOC102557192 Neighboring gene small nucleolar RNA, C/D box 34

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables dolichyl-diphosphooligosaccharide-protein glycotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables dolichyl-diphosphooligosaccharide-protein glycotransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables dolichyl-diphosphooligosaccharide-protein glycotransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in ERAD pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in co-translational protein modification ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in glycoprotein catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in post-translational protein modification IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in post-translational protein modification ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein N-linked glycosylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein N-linked glycosylation via asparagine IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein N-linked glycosylation via asparagine ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein N-linked glycosylation via asparagine ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in response to unfolded protein ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    part_of oligosaccharyltransferase complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of oligosaccharyltransferase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B
    Names
    STT3B, catalytic subunit of the oligosaccharyltransferase complex
    STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
    source of immunodominant MHC-associated peptides
    NP_001164010.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001170539.1NP_001164010.1  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

      See identical proteins and their annotated locations for NP_001164010.1

      Status: PROVISIONAL

      Source sequence(s)
      BC166740
      UniProtKB/TrEMBL
      A0A8I5ZNT8, A0A9K3Y857, B2RYD7, E9PTQ6
      Related
      ENSRNOP00000017243.6, ENSRNOT00000017243.9
      Conserved Domains (1) summary
      pfam02516
      Location:69561
      STT3; Oligosaccharyl transferase STT3 subunit

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      123806836..123872179 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)