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    Dmkn dermokine [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361548, updated on 9-Dec-2024

    Summary

    Symbol
    Dmknprovided by RGD
    Full Name
    dermokineprovided by RGD
    Primary source
    RGD:1561521
    See related
    EnsemblRapid:ENSRNOG00000055934 AllianceGenome:RGD:1561521
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1561521
    Summary
    Predicted to act upstream of or within cornified envelope assembly. Predicted to be located in extracellular space. Orthologous to human DMKN (dermokine). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 58.2), Brain (RPKM 5.6) and 1 other tissue See more
    Orthologs
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    Genomic context

    See Dmkn in Genome Data Viewer
    Location:
    1q21
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (95140737..95158676)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (86013237..86031243)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (89215266..89229696)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 147 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase, spermatogenic Neighboring gene suprabasin Neighboring gene keratinocyte differentiation associated protein Neighboring gene ribosomal protein L36 like 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in cornified envelope assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within cornified envelope assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001173357.1NP_001166828.1  dermokine precursor

      See identical proteins and their annotated locations for NP_001166828.1

      Status: PROVISIONAL

      Source sequence(s)
      BC166816
      UniProtKB/TrEMBL
      A0A1W2Q687, A6JA22, B2RYK9
      Related
      ENSRNOP00000076175.2, ENSRNOT00000093612.3

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      95140737..95158676
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063266496.1XP_063122566.1  dermokine isoform X1

      UniProtKB/TrEMBL
      A0A1W2Q687, A6JA22, B2RYK9
    2. XM_063266497.1XP_063122567.1  dermokine isoform X2

      UniProtKB/TrEMBL
      A0A0G2K3X0, A6JA22
    3. XM_039081975.2XP_038937903.1  dermokine isoform X2

      UniProtKB/TrEMBL
      A0A0G2K3X0, A6JA22
      Conserved Domains (1) summary
      cd21118
      Location:19500
      dermokine
    4. XM_063266498.1XP_063122568.1  dermokine isoform X3

      UniProtKB/TrEMBL
      A6JA23
      Related
      ENSRNOP00000102409.1, ENSRNOT00000151719.1
    5. XM_039081986.2XP_038937914.1  dermokine isoform X3

      UniProtKB/TrEMBL
      A6JA23
      Conserved Domains (1) summary
      cl11081
      Location:26104
      dermokine