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    Ccdc81 coiled-coil domain containing 81 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 308810, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ccdc81provided by RGD
    Official Full Name
    coiled-coil domain containing 81provided by RGD
    Primary source
    RGD:1306766
    See related
    EnsemblRapid:ENSRNOG00000033733 AllianceGenome:RGD:1306766
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1306766
    Summary
    Predicted to enable DNA binding activity. Predicted to be located in centrosome. Predicted to be active in microtubule organizing center. Orthologous to human CCDC81 (coiled-coil domain containing 81). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 107.7), Lung (RPKM 24.7) and 1 other tissue See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ccdc81 in Genome Data Viewer
    Location:
    1q32
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (153152032..153203586, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (143739472..143791026, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (154064132..154111999, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102549783 Neighboring gene malic enzyme 3 Neighboring gene uncharacterized LOC120099878 Neighboring gene uncharacterized LOC134483752 Neighboring gene MLV-related proviral Env polyprotein-like, pseudogene 17

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Proteomic analysis of mammalian sperm cells identifies new components of the centrosome. Firat-Karalar EN, et al. J Cell Sci, 2014 Oct 1. PMID 25074808, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in centrosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in microtubule organizing center IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 81

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014021.1 → NP_001014043.1  coiled-coil domain-containing protein 81

      See identical proteins and their annotated locations for NP_001014043.1

      Status: PROVISIONAL

      Source sequence(s)
      BC083639
      UniProtKB/Swiss-Prot
      Q5XIN9
      UniProtKB/TrEMBL
      A6I608, D4ADM4
      Related
      ENSRNOP00000080187.2, ENSRNOT00000102115.2
      Conserved Domains (1) summary
      pfam14908
      Location:29 → 159
      DUF4496; Domain of unknown function (DUF4496)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      153152032..153203586 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039113100.2 → XP_038969028.1  coiled-coil domain-containing protein 81 isoform X1

      Conserved Domains (2) summary
      pfam14908
      Location:10 → 93
      DUF4496; Domain of unknown function (DUF4496)
      pfam18289
      Location:103 → 177
      HU-CCDC81_euk_2; CCDC81 eukaryotic HU domain 2
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5XIN9.1 GenPept UniProtKB/Swiss-Prot:Q5XIN9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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    Research Materials