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    Polr2f RNA polymerase II, I and III subunit F [ Rattus norvegicus (Norway rat) ]

    Gene ID: 83503, updated on 9-Dec-2024

    Summary

    Official Symbol
    Polr2fprovided by RGD
    Official Full Name
    RNA polymerase II, I and III subunit Fprovided by RGD
    Primary source
    RGD:708567
    See related
    EnsemblRapid:ENSRNOG00000011214 AllianceGenome:RGD:708567
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable DNA-directed 5'-3' RNA polymerase activity. Predicted to contribute to RNA polymerase I activity; RNA polymerase II activity; and RNA polymerase III activity. Predicted to be involved in tRNA transcription by RNA polymerase III; transcription by RNA polymerase I; and transcription by RNA polymerase II. Predicted to be located in fibrillar center and nucleoplasm. Predicted to be part of RNA polymerase I complex; RNA polymerase II, core complex; and RNA polymerase III complex. Orthologous to human POLR2F (RNA polymerase II, I and III subunit F). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 110.9), Kidney (RPKM 72.3) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Polr2f in Genome Data Viewer
    Location:
    7q34
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (112592977..112604681)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (110712528..110724234)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (120380543..120392214)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 3, subunit L Neighboring gene MICAL-like 1 Neighboring gene similar to human chromosome 22 open reading frame 23 Neighboring gene uncharacterized LOC120093688 Neighboring gene SRY-box transcription factor 10

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding  
    enables DNA-directed 5'-3' RNA polymerase activity PubMed 
    contributes_to RNA polymerase I activity  
    contributes_to RNA polymerase II activity  
    contributes_to RNA polymerase III activity  
    Component Evidence Code Pubs
    part_of RNA polymerase I complex  
    part_of RNA polymerase I complex  
    part_of RNA polymerase I complex PubMed 
    part_of RNA polymerase II, core complex  
    part_of RNA polymerase II, core complex  
    part_of RNA polymerase II, core complex  
    part_of RNA polymerase II, core complex PubMed 
    part_of RNA polymerase III complex  
    part_of RNA polymerase III complex  
    part_of RNA polymerase III complex PubMed 
    located_in fibrillar center  
    located_in fibrillar center  
    located_in nucleoplasm  
    located_in nucleus  
    located_in nucleus  

    General protein information

    Preferred Names
    DNA-directed RNA polymerases I, II, and III subunit RPABC2
    Names
    DNA-directed RNA polymerase II subunit F
    RNA polymerase II subunit F
    RNA polymerases I, II, and III subunit ABC2
    RPB6 homolog
    polymerase (RNA) II (DNA directed) polypeptide F
    polymerase (RNA) II subunit F
    polymerase II
    NP_112625.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031335.3NP_112625.1  DNA-directed RNA polymerases I, II, and III subunit RPABC2

      See identical proteins and their annotated locations for NP_112625.1

      Status: PROVISIONAL

      Source sequence(s)
      AB017711
      UniProtKB/Swiss-Prot
      O88828
      UniProtKB/TrEMBL
      A6HSQ1
      Related
      ENSRNOP00000015009.3, ENSRNOT00000015009.8
      Conserved Domains (1) summary
      PLN00152
      Location:26127
      PLN00152; DNA-directed RNA polymerase; Provisional

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      112592977..112604681
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_355831.5 RNA Sequence

    2. XR_010053048.1 RNA Sequence

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