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    Pld5 phospholipase D family, member 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 289270, updated on 4-Jan-2025

    Summary

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    Official Symbol
    Pld5provided by RGD
    Official Full Name
    phospholipase D family, member 5provided by RGD
    Primary source
    RGD:1562609
    See related
    EnsemblRapid:ENSRNOG00000003997 AllianceGenome:RGD:1562609
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1562609
    Summary
    Predicted to enable catalytic activity. Predicted to be located in membrane. Orthologous to human PLD5 (phospholipase D family member 5). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Biased expression in Brain (RPKM 29.0), Muscle (RPKM 7.5) and 2 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Pld5 in Genome Data Viewer
    Location:
    13q24
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (90426689..90765072, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (87895694..88232868, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (94025696..94355219, complement)

    Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103692325 Neighboring gene exonuclease 1 Neighboring gene beclin 2 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene centrosomal protein 170 Neighboring gene microRNA 350 Neighboring gene SHH signaling and ciliogenesis regulator SDCCAG8 Neighboring gene AKT serine/threonine kinase 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    inactive phospholipase D5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191674.1 → NP_001178603.1  inactive phospholipase D5

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000013
      UniProtKB/TrEMBL
      F1MA92
      Related
      ENSRNOP00000005332.6, ENSRNOT00000005332.8
      Conserved Domains (3) summary
      cd09146
      Location:111 → 273
      PLDc_vPLD5_1; Putative catalytic domain, repeat 1, of inactive veterbrate phospholipase PLD5
      cd09149
      Location:309 → 502
      PLDc_vPLD5_2; Putative catalytic domain, repeat 2, of inactive veterbrate phospholipase PLD5
      PHA02820
      Location:104 → 521
      PHA02820; phospholipase-D-like protein; Provisional

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086031.1 Reference GRCr8

      Range
      90426689..90765072 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039090526.2 → XP_038946454.1  inactive phospholipase D5 isoform X1

      UniProtKB/TrEMBL
      A0A0G2JW24
      Related
      ENSRNOP00000069712.1, ENSRNOT00000078195.3
      Conserved Domains (2) summary
      cd09146
      Location:49 → 211
      PLDc_vPLD5_1; Putative catalytic domain, repeat 1, of inactive veterbrate phospholipase PLD5
      cd09149
      Location:247 → 440
      PLDc_vPLD5_2; Putative catalytic domain, repeat 2, of inactive veterbrate phospholipase PLD5

    2. XM_039090528.2 → XP_038946456.1  inactive phospholipase D5 isoform X3

      UniProtKB/TrEMBL
      A6JGC2
      Conserved Domains (2) summary
      cd09149
      Location:101 → 294
      PLDc_vPLD5_2; Putative catalytic domain, repeat 2, of inactive veterbrate phospholipase PLD5
      cl15239
      Location:1 → 65
      PLDc_SF; Catalytic domain of phospholipase D superfamily proteins

    3. XM_039090527.2 → XP_038946455.1  inactive phospholipase D5 isoform X2

      Conserved Domains (2) summary
      cd09146
      Location:19 → 181
      PLDc_vPLD5_1; Putative catalytic domain, repeat 1, of inactive veterbrate phospholipase PLD5
      cd09149
      Location:217 → 410
      PLDc_vPLD5_2; Putative catalytic domain, repeat 2, of inactive veterbrate phospholipase PLD5
    Nucleotide Protein Strain
    Heading Accession and Version

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