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    Rnf17 ring finger protein 17 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 305908, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Rnf17provided by RGD
    Official Full Name
    ring finger protein 17provided by RGD
    Primary source
    RGD:1310486
    See related
    EnsemblRapid:ENSRNOG00000008059 AllianceGenome:RGD:1310486
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable identical protein binding activity. Predicted to act upstream of or within spermatid development. Predicted to be located in cytoplasm. Orthologous to human RNF17 (ring finger protein 17). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 55.4) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Rnf17 in Genome Data Viewer
    Location:
    15p12
    Exon count:
    38
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (34603448..34741658)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (30487899..30626024)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (36609348..36744750)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene granzyme B Neighboring gene ATPase H+/K+ transporting non-gastric alpha2 subunit Neighboring gene TM2 domain-containing protein 1 pseudogene Neighboring gene centromere protein J Neighboring gene poly (ADP-ribose) polymerase family, member 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within spermatid development ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    RING finger protein 17

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191685.1 → NP_001178614.1  RING finger protein 17

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000015
      UniProtKB/TrEMBL
      A0A8I6GJ74, D3ZLP2
      Related
      ENSRNOP00000090862.2, ENSRNOT00000096665.2
      Conserved Domains (4) summary
      cd04508
      Location:755 → 801
      TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
      pfam00567
      Location:1196 → 1312
      TUDOR; Tudor domain
      cl22851
      Location:30 → 72
      PHD_SF; PHD finger superfamily
      cl23765
      Location:137 → 242
      iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      34603448..34741658
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039093305.2 → XP_038949233.1  RING finger protein 17 isoform X1

      UniProtKB/TrEMBL
      A0A8I6GJ74
      Related
      ENSRNOP00000010795.6, ENSRNOT00000010795.9
      Conserved Domains (7) summary
      smart00502
      Location:137 → 242
      BBC; B-Box C-terminal domain
      cd20414
      Location:490 → 566
      Tudor_TDRD4_rpt1; first Tudor domain found in Tudor domain-containing protein 4 (TDRD4) and similar proteins
      cd20415
      Location:728 → 823
      Tudor_TDRD4_rpt2; second Tudor domain found in Tudor domain-containing protein 4 (TDRD4) and similar proteins
      cd20416
      Location:968 → 1049
      Tudor_TDRD4_rpt3; third Tudor domain found in Tudor domain-containing protein 4 (TDRD4) and similar proteins
      cd20417
      Location:1247 → 1314
      Tudor_TDRD4_rpt4; fourth Tudor domain found in Tudor domain-containing protein 4 (TDRD4) and similar proteins
      cd20418
      Location:1504 → 1608
      Tudor_TDRD4_rpt5; fifth Tudor domain found in Tudor domain-containing protein 4 (TDRD4) and similar proteins
      cl22851
      Location:30 → 72
      PHD_SF; PHD finger superfamily

    2. XM_039093306.2 → XP_038949234.1  RING finger protein 17 isoform X2

      Conserved Domains (5) summary
      smart00502
      Location:137 → 242
      BBC; B-Box C-terminal domain
      cd20414
      Location:490 → 566
      Tudor_TDRD4_rpt1; first Tudor domain found in Tudor domain-containing protein 4 (TDRD4) and similar proteins
      cd20415
      Location:728 → 823
      Tudor_TDRD4_rpt2; second Tudor domain found in Tudor domain-containing protein 4 (TDRD4) and similar proteins
      cd20416
      Location:968 → 1049
      Tudor_TDRD4_rpt3; third Tudor domain found in Tudor domain-containing protein 4 (TDRD4) and similar proteins
      cl22851
      Location:30 → 72
      PHD_SF; PHD finger superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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