Cbln4 cerebellin 4 precursor [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Cbln4provided by RGD
Official Full Name: cerebellin 4 precursorprovided by RGD
Primary source: RGD:1589642
See related: EnsemblRapid:ENSRNOG00000004372 AllianceGenome:RGD:1589642
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in inhibitory synapse assembly and trans-synaptic signaling, modulating synaptic transmission. Predicted to act upstream of or within protein secretion. Predicted to be located in GABA-ergic synapse and extracellular space. Predicted to be active in glutamatergic synapse and synaptic cleft. Orthologous to human CBLN4 (cerebellin 4 precursor). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Restricted expression toward (RPKM 30.9) See more
Orthologs: human mouse all
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Genomic context

Location:: 3q42

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (181218046..181225600, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (160799587..160807143, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (170033166..170040953, complement)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

BE108611 (e-PCR)
- UniSTS:247819

Cbln4 (e-PCR), detects polymorphism
- UniSTS:525887

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in inhibitory synapse assembly	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within protein secretion	ISO Inferred from Sequence Orthology more info
involved_in trans-synaptic signaling, modulating synaptic transmission	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in GABA-ergic synapse	ISO Inferred from Sequence Orthology more info
located_in extracellular region	ISO Inferred from Sequence Orthology more info
located_in extracellular space	ISO Inferred from Sequence Orthology more info
is_active_in glutamatergic synapse	ISO Inferred from Sequence Orthology more info
is_active_in synapse	IBA Inferred from Biological aspect of Ancestor more info
is_active_in synaptic cleft	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: cerebellin-4

Names: cerebellin 4 precursor protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.