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    Scart1 scavenger receptor family member expressed on T-cells 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 293591, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Scart1provided by RGD
    Official Full Name
    scavenger receptor family member expressed on T-cells 1provided by RGD
    Primary source
    RGD:1307378
    See related
    EnsemblRapid:ENSRNOG00000018978 AllianceGenome:RGD:1307378
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Cd163l1; RGD1307378
    Summary
    Predicted to be located in brush border; cytoplasm; and plasma membrane. Orthologous to human SCART1 (scavenger receptor family member expressed on T cells 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 13.4), Thymus (RPKM 11.8) and 5 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Scart1 in Genome Data Viewer
    Location:
    1q41
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (204450386..204462094)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (195020750..195031807)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (212695735..212706986)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 6 subfamily F member 2 Neighboring gene olfactory receptor family 6 subfamily B member 13 Neighboring gene scavenger receptor cysteine-rich domain-containing protein SCART1-like Neighboring gene mitochondrial ribosomal protein L42, pseudogene 1 Neighboring gene olfactory receptor family 13 subfamily A member 19B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Characterization of a novel human scavenger receptor cysteine-rich molecule SCART1 expressed by lymphocytes. Holm D, et al. Immunobiology, 2013 Mar. PMID 22795646
    2. Elevated numbers of SCART1+ gammadelta T cells in skin inflammation and inflammatory bowel disease. Fink DR, et al. Mol Immunol, 2010 May. PMID 20381152
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in brush border ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    scavenger receptor cysteine-rich domain-containing protein SCART1
    Names
    CD163 molecule-like 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106312.1 → NP_001099782.1  scavenger receptor cysteine-rich domain-containing protein SCART1 precursor

      See identical proteins and their annotated locations for NP_001099782.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473953
      UniProtKB/TrEMBL
      A6HXH9, A6HXI0, D3ZR76, D4AEN2
      Related
      ENSRNOP00000045146.3, ENSRNOT00000049269.5
      Conserved Domains (2) summary
      smart00202
      Location:546 → 646
      SR; Scavenger receptor Cys-rich
      pfam00530
      Location:551 → 646
      SRCR; Scavenger receptor cysteine-rich domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      204450386..204462094
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063286462.1 → XP_063142532.1  scavenger receptor cysteine-rich domain-containing protein SCART1 isoform X1

      UniProtKB/TrEMBL
      A6HXH9, A6HXI0, D3ZR76, D4AEN2
    Nucleotide Protein Strain
    Heading Accession and Version

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