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    Elof1 elongation factor 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 691193, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Elof1provided by RGD
    Official Full Name
    elongation factor 1provided by RGD
    Primary source
    RGD:1587399
    See related
    EnsemblRapid:ENSRNOG00000014284 AllianceGenome:RGD:1587399
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309855
    Summary
    Predicted to enable RNA polymerase II complex binding activity. Predicted to be involved in transcription elongation by RNA polymerase II. Predicted to be part of transcription elongation factor complex. Orthologous to human ELOF1 (elongation factor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 479.1), Kidney (RPKM 141.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Elof1 in Genome Data Viewer
    Location:
    8q13
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (28921338..28926612, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (20645336..20650888, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (23125987..23130980, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120094091 Neighboring gene ECSIT signaling integrator Neighboring gene calponin 1 Neighboring gene acid phosphatase 5, tartrate resistant Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class Y like 1 Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class Y

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA polymerase II complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in transcription elongation by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of transcription elongation factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    transcription elongation factor 1 homolog
    Names
    ELF1 homolog, elongation factor 1
    elongation factor 1 homolog (ELF1, S. cerevisiae)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001126098.1 → NP_001119570.1  transcription elongation factor 1 homolog

      See identical proteins and their annotated locations for NP_001119570.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473993
      UniProtKB/TrEMBL
      A6JNZ0, D4AEE9
      Related
      ENSRNOP00000019140.4, ENSRNOT00000019140.7
      Conserved Domains (1) summary
      pfam05129
      Location:20 → 80
      Elf1; Transcription elongation factor Elf1 like

    2. NM_001429182.1 → NP_001416111.1  transcription elongation factor 1 homolog

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A6JNZ0, D4AEE9

    3. NM_001429183.1 → NP_001416112.1  transcription elongation factor 1 homolog

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A6JNZ0, D4AEE9

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      28921338..28926612 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039082187.2 → XP_038938115.2  transcription elongation factor 1 homolog isoform X2

      UniProtKB/TrEMBL
      A0A8I6AF92

    2. XM_063266180.1 → XP_063122250.1  transcription elongation factor 1 homolog isoform X1

    3. XM_008765987.4 → XP_008764209.1  transcription elongation factor 1 homolog isoform X5

      Conserved Domains (1) summary
      pfam05129
      Location:20 → 80
      Elf1; Transcription elongation factor Elf1 like

    4. XM_063266181.1 → XP_063122251.1  transcription elongation factor 1 homolog isoform X4

    5. XM_039082188.2 → XP_038938116.2  transcription elongation factor 1 homolog isoform X3

      UniProtKB/TrEMBL
      A0A8I6AI25
    Nucleotide Protein Strain
    Heading Accession and Version

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