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    Fam185a family with sequence similarity 185, member A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 499979, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fam185aprovided by RGD
    Official Full Name
    family with sequence similarity 185, member Aprovided by RGD
    Primary source
    RGD:1562135
    See related
    EnsemblRapid:ENSRNOG00000048371 AllianceGenome:RGD:1562135
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1562135
    Summary
    Predicted to be located in mitochondrion. Orthologous to human FAM185A (family with sequence similarity 185 member A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 117.2), Muscle (RPKM 88.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Fam185a in Genome Data Viewer
    Location:
    4q11
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (14469165..14555167, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (13542022..13662967, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (10213679..10269999, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene F-box and leucine-rich repeat protein 13 Neighboring gene leucine rich repeat containing 17 Neighboring gene small nucleolar RNA SNORD86 Neighboring gene uncharacterized LOC134486551 Neighboring gene coiled-coil domain containing 146 Neighboring gene fibrinogen-like 2 Neighboring gene uncharacterized LOC120102212

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
    2. Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. Morgenstern M, et al. Cell Metab, 2021 Dec 7. PMID 34800366, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC187429

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein FAM185A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001395612.1 → NP_001382541.1  protein FAM185A

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      A0A8I6AHV7
      Related
      ENSRNOP00000086102.2, ENSRNOT00000101027.2
      Conserved Domains (1) summary
      cl23960
      Location:128 → 256
      DUF4097; Putative adhesin

    RNA

    1. NR_172647.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      14469165..14555167 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039108077.2 → XP_038964005.1  protein FAM185A isoform X4

      UniProtKB/TrEMBL
      A0A8I6ASX3
      Conserved Domains (1) summary
      cl23960
      Location:101 → 202
      DUF4097; Putative adhesin

    2. XM_039108083.2 → XP_038964011.1  protein FAM185A isoform X6

      UniProtKB/TrEMBL
      A0A8I6A565, A0A8I6ASX3
      Conserved Domains (1) summary
      cl23960
      Location:101 → 202
      DUF4097; Putative adhesin

    3. XM_039108075.2 → XP_038964003.1  protein FAM185A isoform X2

      Conserved Domains (1) summary
      cl23960
      Location:101 → 256
      DUF4097; Putative adhesin

    4. XM_039108076.2 → XP_038964004.1  protein FAM185A isoform X3

      Conserved Domains (1) summary
      cl23960
      Location:101 → 256
      DUF4097; Putative adhesin

    5. XM_039108074.2 → XP_038964002.1  protein FAM185A isoform X1

      UniProtKB/TrEMBL
      A0A8I6AMA4
      Related
      ENSRNOP00000097420.2, ENSRNOT00000120183.2
      Conserved Domains (1) summary
      cl23960
      Location:128 → 256
      DUF4097; Putative adhesin

    6. XM_039108081.2 → XP_038964009.1  protein FAM185A isoform X5

      UniProtKB/TrEMBL
      A0A8I6ASX3, B1WBS7, M0RDY2
      Conserved Domains (1) summary
      cl23960
      Location:101 → 202
      DUF4097; Putative adhesin

    7. XM_063286463.1 → XP_063142533.1  protein FAM185A isoform X5

      UniProtKB/TrEMBL
      A0A8I6ASX3, B1WBS7, M0RDY2

    8. XM_039108080.2 → XP_038964008.1  protein FAM185A isoform X5

      UniProtKB/TrEMBL
      A0A8I6ASX3, B1WBS7, M0RDY2
      Related
      ENSRNOP00000067845.2, ENSRNOT00000074662.3
      Conserved Domains (1) summary
      cl23960
      Location:101 → 202
      DUF4097; Putative adhesin

    RNA

    1. XR_005503286.2 RNA Sequence

    2. XR_010065687.1 RNA Sequence

    3. XR_005503285.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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