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    Eef1g eukaryotic translation elongation factor 1 gamma [ Rattus norvegicus (Norway rat) ]

    Gene ID: 293725, updated on 9-Dec-2024

    Summary

    Official Symbol
    Eef1gprovided by RGD
    Official Full Name
    eukaryotic translation elongation factor 1 gammaprovided by RGD
    Primary source
    RGD:1302939
    See related
    EnsemblRapid:ENSRNOG00000020075 AllianceGenome:RGD:1302939
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable translation elongation factor activity. Predicted to be involved in response to virus and translational elongation. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytoplasm and nucleus. Orthologous to human EEF1G (eukaryotic translation elongation factor 1 gamma). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 2690.0), Spleen (RPKM 2395.2) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Eef1g in Genome Data Viewer
    Location:
    1q43
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (215289815..215300421)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (205860713..205871319)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (225163391..225173997)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene metastasis associated 1 family, member 2 Neighboring gene uncharacterized LOC134483968 Neighboring gene terminal uridylyl transferase 1, U6 snRNA-specific Neighboring gene AHNAK nucleoprotein Neighboring gene U4 spliceosomal RNA Neighboring gene ribosomal protein L7a, pseudogene 8

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    Interactions

    General gene information

    Clone Names

    • MGC94929, MGC114210

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in response to virus  
    involved_in translational elongation  
    involved_in translational elongation  
    Component Evidence Code Pubs
    is_active_in cytoplasm  
    located_in cytoplasm  
    located_in endoplasmic reticulum  
    is_active_in nucleus  

    General protein information

    Preferred Names
    elongation factor 1-gamma
    Names
    EF-1-gamma
    eEF-1B gamma

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004223.2NP_001004223.1  elongation factor 1-gamma

      See identical proteins and their annotated locations for NP_001004223.1

      Status: PROVISIONAL

      Source sequence(s)
      BC098895
      UniProtKB/Swiss-Prot
      Q4FZZ5, Q68FR6
      UniProtKB/TrEMBL
      A0A8I6AK06, A6HZY2
      Related
      ENSRNOP00000027305.4, ENSRNOT00000027305.9
      Conserved Domains (4) summary
      cd03181
      Location:91213
      GST_C_EF1Bgamma_like; Glutathione S-transferase C-terminal-like, alpha helical domain of the Gamma subunit of Elongation Factor 1B and similar proteins
      cd03044
      Location:482
      GST_N_EF1Bgamma; GST_N family, Gamma subunit of Elongation Factor 1B (EFB1gamma) subfamily; EF1Bgamma is part of the eukaryotic translation elongation factor-1 (EF1) complex which plays a central role in the elongation cycle during protein biosynthesis. EF1 consists of ...
      TIGR01262
      Location:5187
      maiA; maleylacetoacetate isomerase
      pfam00647
      Location:275381
      EF1G; Elongation factor 1 gamma, conserved domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      215289815..215300421
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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