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    Swi5 SWI5 homologous recombination repair protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 499779, updated on 27-Dec-2024

    Summary

    Official Symbol
    Swi5provided by RGD
    Official Full Name
    SWI5 homologous recombination repair proteinprovided by RGD
    Primary source
    RGD:1559966
    See related
    AllianceGenome:RGD:1559966
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in cellular response to ionizing radiation and double-strand break repair via homologous recombination. Predicted to be located in nucleus. Predicted to be part of Swi5-Sfr1 complex. Orthologous to human SWI5 (SWI5 homologous recombination repair protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 701.0), Thymus (RPKM 619.8) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Swi5 in Genome Data Viewer
    Location:
    3p12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (35972436..35981658, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (15574687..15583760, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (11307981..11317049, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene protein-O-mannosyltransferase 1 Neighboring gene uridine-cytidine kinase 1 Neighboring gene uncharacterized LOC134486071 Neighboring gene golgin A2 Neighboring gene dynamin 1 Neighboring gene U1 spliceosomal RNA

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in cellular response to ionizing radiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to ionizing radiation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in double-strand break repair via homologous recombination IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in double-strand break repair via homologous recombination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in double-strand break repair via homologous recombination ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    part_of Swi5-Sfr1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of Swi5-Sfr1 complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of Swi5-Sfr1 complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    DNA repair protein SWI5 homolog
    Names
    protein SAE3 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001246661.1NP_001233590.1  DNA repair protein SWI5 homolog

      See identical proteins and their annotated locations for NP_001233590.1

      Status: PROVISIONAL

      Source sequence(s)
      BC082799
      UniProtKB/Swiss-Prot
      Q63ZV7
      UniProtKB/TrEMBL
      A6JU49
      Conserved Domains (1) summary
      pfam07061
      Location:1388
      Swi5

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      35972436..35981658 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063284351.1XP_063140421.1  DNA repair protein SWI5 homolog isoform X1

      UniProtKB/Swiss-Prot
      Q63ZV7
      UniProtKB/TrEMBL
      A6JU49