U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    Hivep2 HIVEP zinc finger 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 29721, updated on 9-Dec-2024

    Summary

    Official Symbol
    Hivep2provided by RGD
    Official Full Name
    HIVEP zinc finger 2provided by RGD
    Primary source
    RGD:61988
    See related
    EnsemblRapid:ENSRNOG00000011015 AllianceGenome:RGD:61988
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    MIBP1
    Summary
    Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 43. Orthologous to human HIVEP2 (HIVEP zinc finger 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 142.9), Thymus (RPKM 109.4) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Hivep2 in Genome Data Viewer
    Location:
    1p13
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (10176880..10376089)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (8358205..8555993)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (8129354..8333890)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene cofilin 1, pseudogene 8 Neighboring gene uncharacterized LOC134484948 Neighboring gene androgen-induced 1 Neighboring gene ribosomal protein L13A, pseudogene 9 Neighboring gene transfer RNA alanine (anticodon AGC) 27 Neighboring gene similar to human chromosome 3 open reading frame 38

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in nucleoplasm  
    located_in nucleoplasm  
    is_active_in nucleus  

    General protein information

    Preferred Names
    human immunodeficiency virus type I enhancer-binding protein 2 homolog
    Names
    DNA-binding protein AGIE-BP1
    MIBP-1
    angiotensinogen gene-inducible enhancer-binding protein 1
    c-myc intron binding protein 1
    human immunodeficiency virus type 1 enhancer-binding protein 2
    human immunodeficiency virus type I enhancer binding protein 2
    myc intron-binding protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_024137.1NP_077051.1  human immunodeficiency virus type I enhancer-binding protein 2 homolog

      See identical proteins and their annotated locations for NP_077051.1

      Status: PROVISIONAL

      Source sequence(s)
      D37951
      UniProtKB/Swiss-Prot
      Q00900, Q63725
      Related
      ENSRNOP00000015131.2, ENSRNOT00000015131.6
      Conserved Domains (5) summary
      sd00017
      Location:191211
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:17921812
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:18431877
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:17901812
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:204228
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      10176880..10376089
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039109867.2XP_038965795.1  human immunodeficiency virus type I enhancer-binding protein 2 homolog isoform X1

      UniProtKB/TrEMBL
      A6JP69, G3V7H8
      Conserved Domains (8) summary
      PTZ00449
      Location:20242167
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      PTZ00441
      Location:824935
      PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
      sd00017
      Location:191211
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:17921812
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:18431877
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:17901812
      zf-C2H2; Zinc finger, C2H2 type
      pfam12171
      Location:18181842
      zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding
      pfam13465
      Location:204228
      zf-H2C2_2; Zinc-finger double domain
    2. XM_063287903.1XP_063143973.1  human immunodeficiency virus type I enhancer-binding protein 2 homolog isoform X1

      UniProtKB/TrEMBL
      A6JP69, G3V7H8
    3. XM_039109863.2XP_038965791.1  human immunodeficiency virus type I enhancer-binding protein 2 homolog isoform X1

      UniProtKB/TrEMBL
      A6JP69, G3V7H8
      Conserved Domains (8) summary
      PTZ00449
      Location:20242167
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      PTZ00441
      Location:824935
      PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
      sd00017
      Location:191211
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:17921812
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:18431877
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:17901812
      zf-C2H2; Zinc finger, C2H2 type
      pfam12171
      Location:18181842
      zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding
      pfam13465
      Location:204228
      zf-H2C2_2; Zinc-finger double domain
    4. XM_039109870.2XP_038965798.1  human immunodeficiency virus type I enhancer-binding protein 2 homolog isoform X1

      UniProtKB/TrEMBL
      A6JP69, G3V7H8
      Conserved Domains (8) summary
      PTZ00449
      Location:20242167
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      PTZ00441
      Location:824935
      PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
      sd00017
      Location:191211
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:17921812
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:18431877
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:17901812
      zf-C2H2; Zinc finger, C2H2 type
      pfam12171
      Location:18181842
      zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding
      pfam13465
      Location:204228
      zf-H2C2_2; Zinc-finger double domain
    5. XM_039109882.2XP_038965810.1  human immunodeficiency virus type I enhancer-binding protein 2 homolog isoform X1

      UniProtKB/TrEMBL
      A6JP69, G3V7H8
      Conserved Domains (8) summary
      PTZ00449
      Location:20242167
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      PTZ00441
      Location:824935
      PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
      sd00017
      Location:191211
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:17921812
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:18431877
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:17901812
      zf-C2H2; Zinc finger, C2H2 type
      pfam12171
      Location:18181842
      zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding
      pfam13465
      Location:204228
      zf-H2C2_2; Zinc-finger double domain
    6. XM_039109890.2XP_038965818.1  human immunodeficiency virus type I enhancer-binding protein 2 homolog isoform X1

      UniProtKB/TrEMBL
      A6JP69, G3V7H8
      Conserved Domains (8) summary
      PTZ00449
      Location:20242167
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      PTZ00441
      Location:824935
      PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
      sd00017
      Location:191211
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:17921812
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:18431877
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:17901812
      zf-C2H2; Zinc finger, C2H2 type
      pfam12171
      Location:18181842
      zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding
      pfam13465
      Location:204228
      zf-H2C2_2; Zinc-finger double domain
    7. XM_039109872.2XP_038965800.1  human immunodeficiency virus type I enhancer-binding protein 2 homolog isoform X1

      UniProtKB/TrEMBL
      A6JP69, G3V7H8
      Conserved Domains (8) summary
      PTZ00449
      Location:20242167
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      PTZ00441
      Location:824935
      PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
      sd00017
      Location:191211
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:17921812
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:18431877
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:17901812
      zf-C2H2; Zinc finger, C2H2 type
      pfam12171
      Location:18181842
      zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding
      pfam13465
      Location:204228
      zf-H2C2_2; Zinc-finger double domain
    8. XM_063287906.1XP_063143976.1  human immunodeficiency virus type I enhancer-binding protein 2 homolog isoform X1

      UniProtKB/TrEMBL
      A6JP69, G3V7H8
    9. XM_039109885.2XP_038965813.1  human immunodeficiency virus type I enhancer-binding protein 2 homolog isoform X1

      UniProtKB/TrEMBL
      A6JP69, G3V7H8
      Conserved Domains (8) summary
      PTZ00449
      Location:20242167
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      PTZ00441
      Location:824935
      PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
      sd00017
      Location:191211
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:17921812
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:18431877
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:17901812
      zf-C2H2; Zinc finger, C2H2 type
      pfam12171
      Location:18181842
      zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding
      pfam13465
      Location:204228
      zf-H2C2_2; Zinc-finger double domain
    10. XM_063287884.1XP_063143954.1  human immunodeficiency virus type I enhancer-binding protein 2 homolog isoform X1

      UniProtKB/TrEMBL
      A6JP69, G3V7H8
    External link. Please review our privacy policy.