U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    Crybb1 crystallin, beta B1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 25421, updated on 9-Dec-2024

    Summary

    Official Symbol
    Crybb1provided by RGD
    Official Full Name
    crystallin, beta B1provided by RGD
    Primary source
    RGD:2416
    See related
    EnsemblRapid:ENSRNOG00000047653 AllianceGenome:RGD:2416
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    CRYB1; CRYB11
    Summary
    A structural constituent of eye lens. Predicted to be involved in lens development in camera-type eye and visual perception. Human ortholog(s) of this gene implicated in cataract and cataract 17 multiple types. Orthologous to human CRYBB1 (crystallin beta B1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 46.1), Brain (RPKM 7.9) and 2 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Crybb1 in Genome Data Viewer
    Location:
    12q16
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (50030146..50043756, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (44369734..44383344, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (50390939..50404550, complement)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene tuftelin interacting protein 11 Neighboring gene SRR1 domain containing Neighboring gene tyrosylprotein sulfotransferase 2 Neighboring gene crystallin, beta A4 Neighboring gene uncharacterized LOC134481212 Neighboring gene myocardial infarction associated transcript Neighboring gene uncharacterized LOC120095864

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in lens development in camera-type eye  
    involved_in visual perception  

    General protein information

    Preferred Names
    beta-crystallin B1
    Names
    beta-B1 crystallin

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_012936.3NP_037068.2  beta-crystallin B1

      See identical proteins and their annotated locations for NP_037068.2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/Swiss-Prot
      A0JN26, P02523, Q9JHV9
      UniProtKB/TrEMBL
      A6J266
      Related
      ENSRNOP00000064741.1, ENSRNOT00000073072.4
      Conserved Domains (1) summary
      pfam00030
      Location:148230
      Crystall; Beta/Gamma crystallin

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      50030146..50043756 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    External link. Please review our privacy policy.