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    Mycbpap Mycbp associated protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 494192, updated on 9-Dec-2024

    Summary

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    Symbol
    Mycbpapprovided by RGD
    Full Name
    Mycbp associated proteinprovided by RGD
    Primary source
    RGD:1359123
    See related
    EnsemblRapid:ENSRNOG00000042912 AllianceGenome:RGD:1359123
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    COD106
    Summary
    Predicted to enable clathrin binding activity and phospholipid binding activity. Involved in chemical synaptic transmission. Predicted to be located in cytoplasm. Predicted to be part of clathrin vesicle coat. Predicted to be active in endosome and plasma membrane. Orthologous to human MYCBPAP (MYCBP associated protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 99.6), Heart (RPKM 73.6) and 5 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Mycbpap in Genome Data Viewer
    Location:
    10q26
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (79947200..79967857, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (79450319..79470977, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (82232105..82253649, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene spermatogenesis associated 20 Neighboring gene epsin 3 Neighboring gene uncharacterized LOC108352211 Neighboring gene radical S-adenosyl methionine domain containing 1 Neighboring gene acyl-CoA synthetase family member 2 Neighboring gene chondroadherin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Cod106, a novel synaptic protein expressed in sensory hair cells of the inner ear and in CNS neurons. Reisinger E, et al. Mol Cell Neurosci, 2005 Jan. PMID 15607946
    2. AMAP-1, a novel testis-specific AMY-1-binding protein, is differentially expressed during the course of spermatogenesis. Yukitake H, et al. Biochim Biophys Acta, 2002 Aug 19. PMID 12151104
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables clathrin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phospholipid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in chemical synaptic transmission IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in spermatogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in spermatogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    part_of clathrin vesicle coat IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extrinsic component of plasma membrane TAS
    Traceable Author Statement
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    MYCBP-associated protein
    Names
    cochlea derived protein of 106 kDa
    organ of Corti membrane-associated protein of 106 kDa

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009482.2 → NP_001009482.2  MYCBP-associated protein isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A0A0G2K1H9

    2. NM_001395044.2 → NP_001381973.1  MYCBP-associated protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/Swiss-Prot
      Q69CM6, Q69CM7
      Related
      ENSRNOP00000071847.3, ENSRNOT00000086261.3

    3. NM_001415761.1 → NP_001402690.1  MYCBP-associated protein isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/Swiss-Prot
      Q69CM6, Q69CM7
      UniProtKB/TrEMBL
      F1LPD4

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      79947200..79967857 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039086538.2 → XP_038942466.1  MYCBP-associated protein isoform X5

      UniProtKB/TrEMBL
      A0A0G2K1H9
      Conserved Domains (1) summary
      pfam14646
      Location:187 → 602
      MYCBPAP; MYCBP-associated protein family

    2. XM_039086534.2 → XP_038942462.1  MYCBP-associated protein isoform X1

      UniProtKB/Swiss-Prot
      Q69CM6, Q69CM7
      Related
      ENSRNOP00000107004.1, ENSRNOT00000125400.1
      Conserved Domains (1) summary
      pfam14646
      Location:279 → 694
      MYCBPAP; MYCBP-associated protein family

    3. XM_039086536.2 → XP_038942464.1  MYCBP-associated protein isoform X4

      UniProtKB/Swiss-Prot
      Q69CM6, Q69CM7
      Related
      ENSRNOP00000062686.4, ENSRNOT00000066132.5
      Conserved Domains (1) summary
      pfam14646
      Location:195 → 610
      MYCBPAP; MYCBP-associated protein family

    4. XM_063269578.1 → XP_063125648.1  MYCBP-associated protein isoform X2

      UniProtKB/Swiss-Prot
      Q69CM6, Q69CM7

    5. XM_063269579.1 → XP_063125649.1  MYCBP-associated protein isoform X3

      UniProtKB/Swiss-Prot
      Q69CM6, Q69CM7
      UniProtKB/TrEMBL
      M0RBQ9
      Related
      ENSRNOP00000067004.2, ENSRNOT00000075795.5

    RNA

    1. XR_010055221.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q69CM7.1 GenPept UniProtKB/Swiss-Prot:Q69CM7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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