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    Fbxo41 F-box protein 41 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 312504, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fbxo41provided by RGD
    Official Full Name
    F-box protein 41provided by RGD
    Primary source
    RGD:1566130
    See related
    EnsemblRapid:ENSRNOG00000033202 AllianceGenome:RGD:1566130
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1566130
    Summary
    Orthologous to human FBXO41 (F-box protein 41). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 89.7), Adrenal (RPKM 19.8) and 1 other tissue See more
    Orthologs
    human mouse all
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    Genomic context

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    See Fbxo41 in Genome Data Viewer
    Location:
    4q34
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (119565012..119597042, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (118007517..118039547, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (117255143..117285228, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene protease-associated domain containing 1 Neighboring gene chaperonin containing TCP1 subunit 7 Neighboring gene early growth response 4 Neighboring gene uncharacterized LOC134486601

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system. Ebstein F, et al. Int J Biochem Cell Biol, 2009 May. PMID 19028597

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    F-box only protein 41

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107871.3 → NP_001101341.1  F-box only protein 41

      See identical proteins and their annotated locations for NP_001101341.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      A0A0G2K9A9, A6IAS7, D3ZT20
      Related
      ENSRNOP00000112418.1, ENSRNOT00000162245.1
      Conserved Domains (4) summary
      PHA03307
      Location:372 → 555
      PHA03307; transcriptional regulator ICP4; Provisional
      COG1196
      Location:195 → 346
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      sd00034
      Location:657 → 683
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:555 → 590
      F-box-like

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      119565012..119597042 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039107602.2 → XP_038963530.1  F-box only protein 41 isoform X1

      UniProtKB/TrEMBL
      A0A0G2K9A9, A6IAS7, D3ZT20
      Related
      ENSRNOP00000042876.6, ENSRNOT00000043201.7
      Conserved Domains (4) summary
      PHA03307
      Location:372 → 555
      PHA03307; transcriptional regulator ICP4; Provisional
      COG1196
      Location:195 → 346
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      sd00034
      Location:657 → 683
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:555 → 590
      F-box-like

    2. XM_039107603.2 → XP_038963531.1  F-box only protein 41 isoform X1

      UniProtKB/TrEMBL
      A0A0G2K9A9, A6IAS7, D3ZT20
      Conserved Domains (4) summary
      PHA03307
      Location:372 → 555
      PHA03307; transcriptional regulator ICP4; Provisional
      COG1196
      Location:195 → 346
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      sd00034
      Location:657 → 683
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:555 → 590
      F-box-like
    Nucleotide Protein Strain
    Heading Accession and Version

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