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    Cped1 cadherin-like and PC-esterase domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500046, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cped1provided by RGD
    Official Full Name
    cadherin-like and PC-esterase domain containing 1provided by RGD
    Primary source
    RGD:1563491
    See related
    EnsemblRapid:ENSRNOG00000021840 AllianceGenome:RGD:1563491
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be located in endoplasmic reticulum. Orthologous to human CPED1 (cadherin like and PC-esterase domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 212.4), Adrenal (RPKM 181.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Cped1 in Genome Data Viewer
    Location:
    4q22
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (51482497..51755440)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (50516712..50789651)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (49055988..49333729)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene cytochrome c oxidase subunit 6C-2-like Neighboring gene inhibitor of growth family, member 3 Neighboring gene Wnt family member 16 Neighboring gene FAM3 metabolism regulating signaling molecule C

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC112827

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    cadherin-like and PC-esterase domain containing 1; cadherin-like and PC-esterase domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001431795.1 → NP_001418724.1  cadherin-like and PC-esterase domain containing 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      A0A0G2QC10, A0A8I6AHU9

    2. NM_001431796.1 → NP_001418725.1  cadherin-like and PC-esterase domain containing 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      A0A0G2QC10

    3. NM_001431797.1 → NP_001418726.1  cadherin-like and PC-esterase domain containing 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      A0A0G2QC10

    4. NM_001431798.1 → NP_001418727.1  cadherin-like and PC-esterase domain containing 1 isoform 4

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      51482497..51755440
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039108608.2 → XP_038964536.1  cadherin-like and PC-esterase domain-containing protein 1 isoform X3

      Conserved Domains (1) summary
      pfam12733
      Location:576 → 663
      Cadherin-like; Cadherin-like beta sandwich domain

    2. XM_002729287.6 → XP_002729333.2  cadherin-like and PC-esterase domain-containing protein 1 isoform X1

      Related
      ENSRNOP00000092551.1, ENSRNOT00000105639.2
      Conserved Domains (2) summary
      pfam12733
      Location:582 → 663
      Cadherin-like; Cadherin-like beta sandwich domain
      pfam13839
      Location:757 → 1017
      PC-Esterase; GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p

    3. XM_039108607.2 → XP_038964535.1  cadherin-like and PC-esterase domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A0G2QC10
      Conserved Domains (1) summary
      pfam12733
      Location:419 → 506
      Cadherin-like; Cadherin-like beta sandwich domain

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001037213.1: Suppressed sequence

      Description
      NM_001037213.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.
    Nucleotide Protein Strain
    Heading Accession and Version

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