Asz1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Asz1provided by RGD
Official Full Name: ankyrin repeat, SAM and basic leucine zipper domain containing 1provided by RGD
Primary source: RGD:621579
See related: AllianceGenome:RGD:621579
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Gasz
Summary: Predicted to be involved in male meiotic nuclear division; spermatogenesis; and transposable element silencing. Predicted to be located in cytoplasm. Predicted to be active in pi-body. Orthologous to human ASZ1 (ankyrin repeat, SAM and basic leucine zipper domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Restricted expression toward (RPKM 38.6) See more
Orthologs: human mouse all
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Genomic context

Location:: 4q22

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	4	NC_086022.1 (47366373..47421976, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	4	NC_051339.1 (46400485..46456085, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	4	NC_005103.4 (45358574..45414177, complement)

Chromosome 4 - NC_086022.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in cell differentiation	IEA Inferred from Electronic Annotation more info
involved_in male meiotic nuclear division	ISO Inferred from Sequence Orthology more info
involved_in regulatory ncRNA-mediated gene silencing	IEA Inferred from Electronic Annotation more info
involved_in spermatogenesis	ISO Inferred from Sequence Orthology more info
involved_in transposable element silencing	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
is_active_in pi-body	IBA Inferred from Biological aspect of Ancestor more info
located_in pi-body	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_130750.1 → NP_570106.1 ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1

See identical proteins and their annotated locations for NP_570106.1

Status: PROVISIONAL

Source sequence(s)

AF461260

UniProtKB/TrEMBL

A0A0G2K840, A6IE39, Q8VHF9

Conserved Domains (4) summary

cd09521
Location:273 → 333

SAM_ASZ1; SAM domain of ASZ1 subfamily

COG0666
Location:78 → 214

ANKYR; Ankyrin repeat [Signal transduction mechanisms]

sd00045
Location:151 → 179

ANK; ANK repeat [structural motif]

pfam13637
Location:47 → 99

Ank_4; Ankyrin repeats (many copies)