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    Slc39a10 solute carrier family 39 member 10 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363229, updated on 27-Dec-2024

    Summary

    Official Symbol
    Slc39a10provided by RGD
    Official Full Name
    solute carrier family 39 member 10provided by RGD
    Primary source
    RGD:1307321
    See related
    EnsemblRapid:ENSRNOG00000011677 AllianceGenome:RGD:1307321
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable monoatomic cation:bicarbonate symporter activity; protein tyrosine phosphatase activator activity; and zinc ion transmembrane transporter activity. Predicted to be involved in epithelial to mesenchymal transition; intracellular monoatomic cation homeostasis; and zinc ion import across plasma membrane. Predicted to act upstream of or within several processes, including intracellular zinc ion homeostasis; positive regulation of B cell proliferation; and positive regulation of B cell receptor signaling pathway. Predicted to be located in apical plasma membrane. Predicted to be active in plasma membrane. Orthologous to human SLC39A10 (solute carrier family 39 member 10). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 153.6), Testes (RPKM 58.1) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Slc39a10 in Genome Data Viewer
    Location:
    9q31
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (62331281..62454754)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (54836841..54960325)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (59947562..60070549)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene protein associated with LIN7 1, MAGUK p55 family member, pseudogene 1 Neighboring gene enolase 1, pseudogene 2 Neighboring gene uncharacterized LOC120094685 Neighboring gene dynein, axonemal, heavy chain 7 Neighboring gene uncharacterized LOC120094686 Neighboring gene serine/threonine kinase 17b

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in apical plasma membrane  
    is_active_in plasma membrane  
    located_in plasma membrane  

    General protein information

    Preferred Names
    zinc transporter ZIP10
    Names
    solute carrier family 39 (zinc transporter), member 10

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108796.2 → NP_001102266.2  zinc transporter ZIP10

      See identical proteins and their annotated locations for NP_001102266.2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A0A1W2Q626, A6INY6
      Related
      ENSRNOP00000076105.1, ENSRNOT00000093748.3
      Conserved Domains (1) summary
      pfam02535
      Location:406 → 822
      Zip; ZIP Zinc transporter

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      62331281..62454754
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063267375.1 → XP_063123445.1  zinc transporter ZIP10 isoform X2

      UniProtKB/TrEMBL
      A0A1W2Q626, A6INY6
    2. XM_006244936.5 → XP_006244998.1  zinc transporter ZIP10 isoform X1

      See identical proteins and their annotated locations for XP_006244998.1

      UniProtKB/TrEMBL
      D4A517
      Related
      ENSRNOP00000016262.6, ENSRNOT00000016262.9
      Conserved Domains (1) summary
      pfam02535
      Location:416 → 832
      Zip; ZIP Zinc transporter
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