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    Arl15 ARF like GTPase 15 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 689079, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Arl15provided by RGD
    Official Full Name
    ARF like GTPase 15provided by RGD
    Primary source
    RGD:1597407
    See related
    EnsemblRapid:ENSRNOG00000068448 AllianceGenome:RGD:1597407
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Arfrp2
    Summary
    Predicted to enable GTP binding activity and GTPase activity. Orthologous to human ARL15 (ADP ribosylation factor like GTPase 15). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 86.0), Lung (RPKM 80.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Arl15 in Genome Data Viewer
    Location:
    2q14
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (47171377..47555666)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (45438221..45822562)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (45668852..46053167)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120100714 Neighboring gene eukaryotic translation initiation factor 1-like Neighboring gene NOP16 nucleolar protein, pseudogene 4 Neighboring gene biliverdin reductase A, pseudogene 1 Neighboring gene uncharacterized LOC120100716 Neighboring gene NADH:ubiquinone oxidoreductase subunit S4 Neighboring gene transfer RNA threonine (anticodon AGU) 8 Neighboring gene uncharacterized LOC120100717 Neighboring gene follistatin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
    2. Large-scale proteomics and phosphoproteomics of urinary exosomes. Gonzales PA, et al. J Am Soc Nephrol, 2009 Feb. PMID 19056867, Free PMC Article
    3. In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Principe S, et al. Proteomics, 2013 May. PMID 23533145, Free PMC Article
    4. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ADP-ribosylation factor-like protein 15
    Names
    ADP-ribosylation factor like GTPase 15
    ADP-ribosylation factor related protein 2
    ADP-ribosylation factor-like 15

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001399590.1 → NP_001386519.1  ADP-ribosylation factor-like protein 15

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A0A8I5ZSX7, A6I5R8, F1M6C4
      Related
      ENSRNOP00000077797.1, ENSRNOT00000112044.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      47171377..47555666
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039103515.2 → XP_038959443.1  ADP-ribosylation factor-like protein 15 isoform X4

      UniProtKB/TrEMBL
      A0A8I5ZSX7
      Conserved Domains (1) summary
      cl38936
      Location:34 → 214
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    2. XM_063282576.1 → XP_063138646.1  ADP-ribosylation factor-like protein 15 isoform X5

      UniProtKB/TrEMBL
      A0A8I5ZSX7
      Related
      ENSRNOP00000105985.1, ENSRNOT00000155468.1

    3. XM_063282575.1 → XP_063138645.1  ADP-ribosylation factor-like protein 15 isoform X1

    4. XM_039103513.2 → XP_038959441.1  ADP-ribosylation factor-like protein 15 isoform X3

      Conserved Domains (1) summary
      cl38936
      Location:87 → 207
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    5. XM_039103512.2 → XP_038959440.1  ADP-ribosylation factor-like protein 15 isoform X2

      Related
      ENSRNOP00000101061.1, ENSRNOT00000123569.1
      Conserved Domains (1) summary
      cl38936
      Location:87 → 246
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    6. XM_063282577.1 → XP_063138647.1  ADP-ribosylation factor-like protein 15 isoform X6

      UniProtKB/TrEMBL
      A0A8I5ZSX7
      Related
      ENSRNOP00000106119.1, ENSRNOT00000141574.1
    Nucleotide Protein Strain
    Heading Accession and Version

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