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    Zfp658 zinc finger protein 658 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 102546648, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zfp658provided by RGD
    Official Full Name
    zinc finger protein 658provided by RGD
    Primary source
    RGD:7541917
    See related
    EnsemblRapid:ENSRNOG00000023233 AllianceGenome:RGD:7541917
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 36.9), Kidney (RPKM 29.8) and 9 other tissues See more
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    Genomic context

    See Zfp658 in Genome Data Viewer
    Location:
    1q22
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (103129001..103143510)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (93992467..94005689)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (99483176..99496427)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene SIGLEC family like 1 Neighboring gene CD33 molecule Neighboring gene zinc finger protein 719 Neighboring gene zinc finger protein 819 Neighboring gene uncharacterized LOC120099801 Neighboring gene CEA cell adhesion molecule 18

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein LOC102546648
    Names
    zinc finger protein 175
    zinc finger protein 175-like
    zinc finger protein 658-like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001420023.1NP_001406952.1  uncharacterized protein LOC102546648

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      M0RCK0

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      103129001..103143510
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008759440.4XP_008757662.1  uncharacterized protein LOC102546648 isoform X1

      See identical proteins and their annotated locations for XP_008757662.1

      UniProtKB/TrEMBL
      M0RCK0
      Conserved Domains (4) summary
      smart00349
      Location:2380
      KRAB; krueppel associated box
      COG5048
      Location:378813
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:313400
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:634654
      ZF_C2H2; C2H2 Zn finger [structural motif]
    2. XM_008759441.4XP_008757663.1  uncharacterized protein LOC102546648 isoform X1

      See identical proteins and their annotated locations for XP_008757663.1

      UniProtKB/TrEMBL
      M0RCK0
      Related
      ENSRNOP00000067320.1, ENSRNOT00000074820.3
      Conserved Domains (4) summary
      smart00349
      Location:2380
      KRAB; krueppel associated box
      COG5048
      Location:378813
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:313400
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:634654
      ZF_C2H2; C2H2 Zn finger [structural motif]