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    Asphd2 aspartate beta-hydroxylase domain containing 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 364948, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Asphd2provided by RGD
    Official Full Name
    aspartate beta-hydroxylase domain containing 2provided by RGD
    Primary source
    RGD:1306020
    See related
    EnsemblRapid:ENSRNOG00000061004 AllianceGenome:RGD:1306020
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1306020
    Summary
    Predicted to enable dioxygenase activity and metal ion binding activity. Predicted to be located in membrane. Orthologous to human ASPHD2 (aspartate beta-hydroxylase domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 45.9) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Asphd2 in Genome Data Viewer
    Location:
    12q16
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (49908539..49919060)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (44248132..44258653)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (50269347..50279855)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene myosin XVIIIb Neighboring gene U6 spliceosomal RNA Neighboring gene seizure related 6 homolog like Neighboring gene coiled-coil domain containing 121 like 2 Neighboring gene coiled-coil domain-containing protein 121-like Neighboring gene HPS4, biogenesis of lysosomal organelles complex 3 subunit 2 Neighboring gene tuftelin interacting protein 11 Neighboring gene SRR1 domain containing

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC105590

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables dioxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    aspartate beta-hydroxylase domain-containing protein 2
    Names
    3110001L23Rik
    calsequestrin-binding protein
    NP_001009716.1
    XP_008767573.1
    XP_017453903.1
    XP_017453904.1
    XP_017453905.1
    XP_017453906.1
    XP_038945577.1
    XP_038945579.1
    XP_038945580.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009716.2 → NP_001009716.1  aspartate beta-hydroxylase domain-containing protein 2

      See identical proteins and their annotated locations for NP_001009716.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/Swiss-Prot
      Q5HZW3
      UniProtKB/TrEMBL
      A6J258
      Conserved Domains (1) summary
      pfam05118
      Location:166 → 325
      Asp_Arg_Hydrox; Aspartyl/Asparaginyl beta-hydroxylase

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      49908539..49919060
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017598414.3 → XP_017453903.1  aspartate beta-hydroxylase domain-containing protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q5HZW3
      UniProtKB/TrEMBL
      A6J258
      Conserved Domains (1) summary
      pfam05118
      Location:166 → 325
      Asp_Arg_Hydrox; Aspartyl/Asparaginyl beta-hydroxylase

    2. XM_017598415.3 → XP_017453904.1  aspartate beta-hydroxylase domain-containing protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q5HZW3
      UniProtKB/TrEMBL
      A6J258
      Conserved Domains (1) summary
      pfam05118
      Location:166 → 325
      Asp_Arg_Hydrox; Aspartyl/Asparaginyl beta-hydroxylase

    3. XM_017598417.3 → XP_017453906.1  aspartate beta-hydroxylase domain-containing protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q5HZW3
      UniProtKB/TrEMBL
      A6J258
      Related
      ENSRNOP00000068694.1, ENSRNOT00000079190.3
      Conserved Domains (1) summary
      pfam05118
      Location:166 → 325
      Asp_Arg_Hydrox; Aspartyl/Asparaginyl beta-hydroxylase

    4. XM_039089652.2 → XP_038945580.1  aspartate beta-hydroxylase domain-containing protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q5HZW3
      UniProtKB/TrEMBL
      A6J258
      Conserved Domains (1) summary
      pfam05118
      Location:166 → 325
      Asp_Arg_Hydrox; Aspartyl/Asparaginyl beta-hydroxylase

    5. XM_017598416.3 → XP_017453905.1  aspartate beta-hydroxylase domain-containing protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q5HZW3
      UniProtKB/TrEMBL
      A6J258
      Conserved Domains (1) summary
      pfam05118
      Location:166 → 325
      Asp_Arg_Hydrox; Aspartyl/Asparaginyl beta-hydroxylase

    6. XM_039089651.2 → XP_038945579.1  aspartate beta-hydroxylase domain-containing protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q5HZW3
      UniProtKB/TrEMBL
      A6J258
      Conserved Domains (1) summary
      pfam05118
      Location:166 → 325
      Asp_Arg_Hydrox; Aspartyl/Asparaginyl beta-hydroxylase

    7. XM_008769351.4 → XP_008767573.1  aspartate beta-hydroxylase domain-containing protein 2 isoform X1

      See identical proteins and their annotated locations for XP_008767573.1

      UniProtKB/Swiss-Prot
      Q5HZW3
      UniProtKB/TrEMBL
      A6J258
      Conserved Domains (1) summary
      pfam05118
      Location:166 → 325
      Asp_Arg_Hydrox; Aspartyl/Asparaginyl beta-hydroxylase

    8. XM_039089649.2 → XP_038945577.1  aspartate beta-hydroxylase domain-containing protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q5HZW3
      UniProtKB/TrEMBL
      A6J258
      Conserved Domains (1) summary
      pfam05118
      Location:166 → 325
      Asp_Arg_Hydrox; Aspartyl/Asparaginyl beta-hydroxylase
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5HZW3.1 GenPept UniProtKB/Swiss-Prot:Q5HZW3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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