Mtg1 mitochondrial ribosome-associated GTPase 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Mtg1provided by RGD
Official Full Name: mitochondrial ribosome-associated GTPase 1provided by RGD
Primary source: RGD:6497155
See related: EnsemblRapid:ENSRNOG00000018860 AllianceGenome:RGD:6497155
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable GTPase activity. Predicted to be involved in mitochondrial translation; regulation of mitochondrial translation; and regulation of respiratory system process. Predicted to be located in mitochondrial inner membrane; mitochondrial ribosome; and nucleoplasm. Predicted to be active in mitochondrion. Orthologous to human MTG1 (mitochondrial ribosome associated GTPase 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Adrenal (RPKM 151.4), Heart (RPKM 119.6) and 9 other tissues See more
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 1q41

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (204361176..204373917)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (194931543..194944278)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (212606753..212619493)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Elevated expression of cellular SYNE1, MMP10, and GTPase1 and their regulatory role in hepatocellular carcinoma progression.
Title: Elevated expression of cellular SYNE1, MMP10, and GTPase1 and their regulatory role in hepatocellular carcinoma progression.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

G45222 (e-PCR)
- UniSTS:106024

BF386524 (e-PCR)
- UniSTS:243767

RH137952 (e-PCR)
- UniSTS:220039

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IBA Inferred from Biological aspect of Ancestor more info
enables GTPase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in mitochondrial translation	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of mitochondrial translation	ISO Inferred from Sequence Orthology more info
involved_in regulation of respiratory system process	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in mitochondrial inner membrane	ISO Inferred from Sequence Orthology more info
located_in mitochondrial matrix	ISO Inferred from Sequence Orthology more info
located_in mitochondrial ribosome	ISO Inferred from Sequence Orthology more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info

General protein information

Go to the top of the page Help

Preferred Names: mitochondrial ribosome-associated GTPase 1

Names: mitochondrial GTPase 1-like; putative GTP-binding protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001401716.1 → NP_001388645.1 mitochondrial ribosome-associated GTPase 1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000001

UniProtKB/TrEMBL

E9PTB3

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086019.1 Reference GRCr8

Range

204361176..204373917

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039101268.2 → XP_038957196.1 mitochondrial ribosome-associated GTPase 1 isoform X2

UniProtKB/TrEMBL

E9PTB3

Conserved Domains (1) summary

cd01856
Location:29 → 180

YlqF; Circularly permuted YlqF GTPase
XM_063283967.1 → XP_063140037.1 mitochondrial ribosome-associated GTPase 1 isoform X3

UniProtKB/TrEMBL

A0A8I6ADG4, E9PTB3

Related

ENSRNOP00000092326.1, ENSRNOT00000109773.2
XM_006230584.4 → XP_006230646.1 mitochondrial ribosome-associated GTPase 1 isoform X1

See identical proteins and their annotated locations for XP_006230646.1

UniProtKB/TrEMBL

E9PTB3

Related

ENSRNOP00000025574.6, ENSRNOT00000025574.9

Conserved Domains (2) summary

cd01856
Location:29 → 206

YlqF; Circularly permuted YlqF GTPase

TIGR03596
Location:29 → 324

GTPase_YlqF; ribosome biogenesis GTP-binding protein YlqF