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    Mypop Myb-related transcription factor, partner of profilin [ Rattus norvegicus (Norway rat) ]

    Gene ID: 499090, updated on 9-Dec-2024

    Summary

    Official Symbol
    Mypopprovided by RGD
    Official Full Name
    Myb-related transcription factor, partner of profilinprovided by RGD
    Primary source
    RGD:1565160
    See related
    AllianceGenome:RGD:1565160
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    P42pop; RGD1565160
    Summary
    Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human MYPOP (Myb related transcription factor, partner of profilin). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 22.7), Muscle (RPKM 12.8) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Mypop in Genome Data Viewer
    Location:
    1q21
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (87767747..87778602)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (78639699..78650555)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (79898492..79909336)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene NOVA alternative splicing regulator 2 Neighboring gene nanos C2HC-type zinc finger 2 Neighboring gene interferon regulatory factor 2 binding protein 1 Neighboring gene forkhead box A3

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in nucleus  
    located_in nucleus  

    General protein information

    Preferred Names
    myb-related transcription factor, partner of profilin
    Names
    Myb protein P42POP

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001395139.1 → NP_001382068.1  myb-related transcription factor, partner of profilin

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A6J8I7, D4AB13
      Conserved Domains (1) summary
      pfam13873
      Location:20 → 96
      Myb_DNA-bind_5; Myb/SANT-like DNA-binding domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      87767747..87778602
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

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