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    Ly6g6e lymphocyte antigen 6 family member G6E [ Rattus norvegicus (Norway rat) ]

    Gene ID: 406866, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ly6g6eprovided by RGD
    Official Full Name
    lymphocyte antigen 6 family member G6Eprovided by RGD
    Primary source
    RGD:1303112
    See related
    EnsemblRapid:ENSRNOG00000027157 AllianceGenome:RGD:1303112
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable acetylcholine receptor activator activity and acetylcholine receptor binding activity. Predicted to be involved in acetylcholine receptor signaling pathway and desensitization of G protein-coupled receptor signaling pathway. Predicted to be located in synapse. Predicted to be active in plasma membrane. Orthologous to human LY6G6E (lymphocyte antigen 6 family member G6E (pseudogene)). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 46.0), Kidney (RPKM 20.8) and 6 other tissues See more
    Orthologs
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    Genomic context

    See Ly6g6e in Genome Data Viewer
    Location:
    20p12
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (3749352..3752578, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (3744999..3749867, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (5063148..5069032)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein S25, pseudogene 2 Neighboring gene lymphocyte antigen 6 family member G6F Neighboring gene lymphocyte antigen 6 family member G6D Neighboring gene lymphocyte antigen 6 family member G6C Neighboring gene megakaryocyte and platelet inhibitory receptor G6b

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in plasma membrane  
    located_in plasma membrane  
    located_in synapse  

    General protein information

    Preferred Names
    lymphocyte antigen 6 complex G6E
    Names
    lymphocyte antigen 6 complex, locus G6E

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001001972.1 → NP_001001972.1  lymphocyte antigen 6 complex G6E precursor

      See identical proteins and their annotated locations for NP_001001972.1

      Status: VALIDATED

      Source sequence(s)
      BX883045
      UniProtKB/TrEMBL
      A0A1L6ZA28, A0A1L6ZA33, A6KTS9, Q6MG57
      Related
      ENSRNOP00000032019.4, ENSRNOT00000037482.5

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      3749352..3752578 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039098955.2 → XP_038954883.1  lymphocyte antigen 6 complex G6E isoform X2

      UniProtKB/TrEMBL
      A0A1L6ZA28, F7FAA3
      Conserved Domains (1) summary
      pfam01064
      Location:57 → 121
      Activin_recp; Activin types I and II receptor domain
    2. XM_039098953.2 → XP_038954881.1  lymphocyte antigen 6 complex G6E isoform X1

      UniProtKB/TrEMBL
      A0A1L6ZA28
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