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    Ifit1bl interferon-induced protein with tetratricopeptide repeats 1B-like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 294090, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ifit1blprovided by RGD
    Official Full Name
    interferon-induced protein with tetratricopeptide repeats 1B-likeprovided by RGD
    Primary source
    RGD:1304872
    See related
    EnsemblRapid:ENSRNOG00000036603 AllianceGenome:RGD:1304872
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ifit1lb
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in defense response to virus. Predicted to be active in cytosol. Orthologous to several human genes including IFIT1B (interferon induced protein with tetratricopeptide repeats 1B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 224.6), Lung (RPKM 57.2) and 8 other tissues See more
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    Genomic context

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    See Ifit1bl in Genome Data Viewer
    Location:
    1q53
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (241535776..241580476, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (232122618..232167317, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (252914684..252959348, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene interferon-induced protein with tetratricopeptide repeats 2 Neighboring gene interferon-induced protein with tetratricopeptide repeats 3 Neighboring gene small nucleolar RNA SNORA71 Neighboring gene interferon-induced protein with tetratricopeptide repeats 1 Neighboring gene solute carrier family 16, member 12 Neighboring gene uncharacterized LOC134485224

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Interferon-induced Ifit proteins: their role in viral pathogenesis. Fensterl V, et al. J Virol, 2015 Mar. PMID 25428874, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response to virus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    interferon-induced protein with tetratricopeptide repeats 1
    Names
    interferon-induced protein with tetratricopeptide repeats 1-like B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001408749.1 → NP_001395678.1  interferon-induced protein with tetratricopeptide repeats 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I6APR1
      Related
      ENSRNOP00000067979.3, ENSRNOT00000076802.3

    2. NM_001408750.1 → NP_001395679.1  interferon-induced protein with tetratricopeptide repeats 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A096MJ38
      Related
      ENSRNOP00000085524.1, ENSRNOT00000095556.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      241535776..241580476 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063287425.1 → XP_063143495.1  interferon-induced protein with tetratricopeptide repeats 1 isoform X1

      UniProtKB/TrEMBL
      A0A8I6APR1

    2. XM_063287426.1 → XP_063143496.1  interferon-induced protein with tetratricopeptide repeats 1 isoform X2

      Related
      ENSRNOP00000095786.2, ENSRNOT00000098477.2
    Nucleotide Protein Strain
    Heading Accession and Version

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