Slc10a6 solute carrier family 10 member 6 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Slc10a6provided by RGD
Official Full Name: solute carrier family 10 member 6provided by RGD
Primary source: RGD:727800
See related: EnsemblRapid:ENSRNOG00000002057 AllianceGenome:RGD:727800
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Soat
Summary: Enables sodium-dependent organic anion transmembrane transporter activity. Involved in sodium-dependent organic anion transport. Predicted to be located in membrane. Orthologous to human SLC10A6 (solute carrier family 10 member 6). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Uterus (RPKM 36.6), Spleen (RPKM 32.2) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 14p22

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	14	NC_086032.1 (6385348..6407532)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	14	NC_051349.1 (6080716..6102902)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	14	NC_005113.4 (7618022..7682377)

Chromosome 14 - NC_086032.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Cloning and analysis of transport function of Soat.
Title: Identification of a sodium-dependent organic anion transporter from rat adrenal gland.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables bile acid:sodium symporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables sodium-dependent organic anion transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in bile acid and bile salt transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in sodium ion transport	IEA Inferred from Electronic Annotation more info
involved_in sodium-dependent organic anion transport	IDA Inferred from Direct Assay more info	PubMed
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: sodium-dependent organic anion transporter

Names: solute carrier family 10 (sodium/bile acid cotransporter family), member 6; solute carrier family 10 (sodium/bile acid cotransporter), member 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_198049.2 → NP_932166.1 sodium-dependent organic anion transporter

See identical proteins and their annotated locations for NP_932166.1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000014

UniProtKB/Swiss-Prot

Q70EX6

Related

ENSRNOP00000072386.1, ENSRNOT00000088508.3

Conserved Domains (1) summary

TIGR00841
Location:34 → 312

bass; bile acid transporter

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086032.1 Reference GRCr8

Range

6385348..6407532

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039091662.2 → XP_038947590.1 sodium-dependent organic anion transporter isoform X1

Conserved Domains (1) summary

cl19217
Location:34 → 196

SBF; Sodium Bile acid symporter family