Gp9 glycoprotein IX (platelet) [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Gp9provided by RGD
Official Full Name: glycoprotein IX (platelet)provided by RGD
Primary source: RGD:1561601
See related: EnsemblRapid:ENSRNOG00000010015 AllianceGenome:RGD:1561601
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in several processes, including blood coagulation, intrinsic pathway; megakaryocyte development; and positive regulation of platelet activation. Predicted to be part of glycoprotein Ib-IX-V complex. Human ortholog(s) of this gene implicated in Bernard-Soulier syndrome. Orthologous to human GP9 (glycoprotein IX platelet). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Spleen (RPKM 63.5), Lung (RPKM 9.4) and 3 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 4q34

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	4	NC_086022.1 (121792842..121794452)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	4	NC_051339.1 (120235500..120237110)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	4	NC_005103.4 (119680671..119682006)

Chromosome 4 - NC_086022.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in blood coagulation	ISO Inferred from Sequence Orthology more info
involved_in blood coagulation, intrinsic pathway	ISO Inferred from Sequence Orthology more info
involved_in cell adhesion	IEA Inferred from Electronic Annotation more info
involved_in megakaryocyte development	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of platelet activation	ISO Inferred from Sequence Orthology more info
involved_in release of sequestered calcium ion into cytosol	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of glycoprotein Ib-IX-V complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: platelet glycoprotein IX

Names: glycoprotein 9 (platelet)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001031825.2 → NP_001026995.1 platelet glycoprotein IX precursor

See identical proteins and their annotated locations for NP_001026995.1

Status: PROVISIONAL

Source sequence(s)

JAXUCZ010000004

UniProtKB/TrEMBL

Q4AEG0

Related

ENSRNOP00000013282.3, ENSRNOT00000013282.7

Conserved Domains (3) summary

smart00013
Location:31 → 65

LRRNT; Leucine rich repeat N-terminal domain

sd00031
Location:58 → 88

LRR_1; leucine-rich repeat [structural motif]

cl15307
Location:97 → 134

TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain