Gpank1 G patch domain and ankyrin repeats 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Gpank1provided by RGD
Official Full Name: G patch domain and ankyrin repeats 1provided by RGD
Primary source: RGD:1303304
See related: EnsemblRapid:ENSRNOG00000000848 AllianceGenome:RGD:1303304
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Bat4
Summary: Predicted to enable nucleic acid binding activity. Orthologous to human GPANK1 (G-patch domain and ankyrin repeats 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 86.7), Spleen (RPKM 82.0) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 20p12

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	20	NC_086038.1 (3702309..3705476, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	20	NC_051355.1 (3697641..3700814, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	20	NC_005119.4 (5113232..5116382)

Chromosome 20 - NC_086038.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: G patch domain and ankyrin repeat-containing protein 1

Names: HLA-B associated transcript 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001034157.2 → NP_001029329.1 G patch domain and ankyrin repeat-containing protein 1

See identical proteins and their annotated locations for NP_001029329.1

Status: VALIDATED

Source sequence(s)

BX883045, CK599826

UniProtKB/TrEMBL

A6KTU5, D3ZX77

Conserved Domains (4) summary

cd00204
Location:102 → 205

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

pfam01585
Location:249 → 293

G-patch; G-patch domain

pfam13637
Location:97 → 155

Ank_4; Ankyrin repeats (many copies)

sd00045
Location:134 → 166

ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086038.1 Reference GRCr8

Range

3702309..3705476 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006256076.5 → XP_006256138.1 G patch domain and ankyrin repeat-containing protein 1 isoform X2

UniProtKB/TrEMBL

A0A096MK87

Conserved Domains (4) summary

cd00204
Location:106 → 209

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

pfam01585
Location:253 → 297

G-patch; G-patch domain

pfam13637
Location:101 → 159

Ank_4; Ankyrin repeats (many copies)

sd00045
Location:138 → 170

ANK; ANK repeat [structural motif]
XM_006256075.5 → XP_006256137.1 G patch domain and ankyrin repeat-containing protein 1 isoform X1

UniProtKB/TrEMBL

A0A8I5ZYU9

Related

ENSRNOP00000098130.2, ENSRNOT00000120466.2

Conserved Domains (4) summary

cd00204
Location:115 → 218

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

pfam01585
Location:262 → 306

G-patch; G-patch domain

pfam13637
Location:110 → 168

Ank_4; Ankyrin repeats (many copies)

sd00045
Location:147 → 179

ANK; ANK repeat [structural motif]
XM_039098997.2 → XP_038954925.1 G patch domain and ankyrin repeat-containing protein 1 isoform X3

Conserved Domains (2) summary

sd00045
Location:147 → 179

ANK; ANK repeat [structural motif]

pfam12796
Location:113 → 200

Ank_2; Ankyrin repeats (3 copies)