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    Zscan26 zinc finger and SCAN domain containing 26 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 266792, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zscan26provided by RGD
    Official Full Name
    zinc finger and SCAN domain containing 26provided by RGD
    Primary source
    RGD:727885
    See related
    EnsemblRapid:ENSRNOG00000053518 AllianceGenome:RGD:727885
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Azf8; Zfp187; Znf187
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Orthologous to human ZSCAN26 (zinc finger and SCAN domain containing 26). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 288.1), Liver (RPKM 187.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zscan26 in Genome Data Viewer
    Location:
    17p11
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (47843822..47863799)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (43148063..43168070)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (45188221..45207846)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120097740 Neighboring gene zinc finger protein with KRAB and SCAN domains 4-like Neighboring gene zinc finger with KRAB and SCAN domains 4 Neighboring gene NFKB activating protein-like Neighboring gene microRNA 1896 Neighboring gene uncharacterized LOC120097923 Neighboring gene piggyBac transposable element derived 1 Neighboring gene zinc finger with KRAB and SCAN domains 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Identification and characterization of zinc finger encoding genes from the tumoral exocrine pancreatic cell line AR42J. Mesa K, et al. Cancer Lett, 1996 Jun 5. PMID 8635150
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger and SCAN domain-containing protein 26
    Names
    zinc finger protein 187
    zinc finger protein 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001400598.1 → NP_001387527.1  zinc finger and SCAN domain-containing protein 26

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      D3ZFY2
      Related
      ENSRNOP00000074883.1, ENSRNOT00000091609.3

    2. NM_001400599.1 → NP_001387528.1  zinc finger and SCAN domain-containing protein 26

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      D3ZFY2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      47843822..47863799
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017600787.3 → XP_017456276.1  zinc finger and SCAN domain-containing protein 26 isoform X1

      UniProtKB/TrEMBL
      D3ZFY2
      Conserved Domains (3) summary
      COG5048
      Location:194 → 422
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:271 → 291
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02605
      Location:43 → 148
      SCAN; SCAN oligomerization domain
    Nucleotide Protein Strain
    Heading Accession and Version

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