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    Dpp7 dipeptidylpeptidase 7 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 83799, updated on 9-Dec-2024

    Summary

    Official Symbol
    Dpp7provided by RGD
    Official Full Name
    dipeptidylpeptidase 7provided by RGD
    Primary source
    RGD:71073
    See related
    EnsemblRapid:ENSRNOG00000012640 AllianceGenome:RGD:71073
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Dpp2
    Summary
    Enables dipeptidyl-peptidase activity. Involved in protein catabolic process. Predicted to be located in Golgi apparatus and lysosome. Predicted to be active in vesicle. Orthologous to human DPP7 (dipeptidyl peptidase 7). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 806.0), Uterus (RPKM 248.9) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Dpp7 in Genome Data Viewer
    Location:
    3p13
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (28563240..28567492, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (8165091..8169343, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (2569135..2573387, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 26 Neighboring gene glutamate ionotropic receptor NMDA type subunit 1 Neighboring gene mannosidase, alpha, class 1B, member 1 Neighboring gene UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 Neighboring gene suppressor APC domain containing 2

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables aminopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables dipeptidyl-peptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables dipeptidyl-peptidase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables dipeptidyl-peptidase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables serine-type exopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within lysosomal protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein catabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lysosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in vesicle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    dipeptidyl peptidase 2
    Names
    DPP II
    dipeptidyl aminopeptidase II
    dipeptidyl peptidase II
    quiescent cell proline dipeptidase
    NP_114179.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031973.1NP_114179.1  dipeptidyl peptidase 2 precursor

      See identical proteins and their annotated locations for NP_114179.1

      Status: PROVISIONAL

      Source sequence(s)
      AB048711
      UniProtKB/Swiss-Prot
      Q9EPB1
      UniProtKB/TrEMBL
      A0A8I6AJ69, A6JT47
      Related
      ENSRNOP00000017271.2, ENSRNOT00000017271.5
      Conserved Domains (1) summary
      cl21494
      Location:48475
      Abhydrolase; alpha/beta hydrolases

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      28563240..28567492 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)